XML 66 R54.htm IDEA: XBRL DOCUMENT v3.22.4
Inventory - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Sep. 30, 2022
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Inventory [Line Items]        
Inventory write-offs, net $ 26,000 $ 26,000 $ 5,133 $ 2,171
Estimate increased the net loss, amount   $ 26,000    
Estimated net loss per share (basic and diluted)   $ 0.33    
Prepayment made for manufacturing services   $ 17,880 13,666  
Inventory   38,791 37,642  
Impairment charge within research and development expenses     3,210  
Impairment charge for the write-off of prepaid manufacturing services no longer deemed to have future benefits     3,200  
Research and development   199,358 363,105 $ 142,759
Prepayments made to a CMO for manufacturing services for UDENYCA   13,000 8,300  
Prepayments made to a CMO For Other Research And Development Pipeline Program   4,900 5,400  
Yusimry Product [Member]        
Inventory [Line Items]        
Inventory   $ 23,700    
CHS-2020        
Inventory [Line Items]        
Research and development     $ 11,200