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Debt Obligations - 2027 Term Loan - Narrative (Details) $ in Thousands		1 Months Ended		3 Months Ended
	Jan. 07, 2019 USD ($)	Mar. 31, 2022 USD ($)	Jan. 31, 2022 USD ($) item	Mar. 31, 2023 USD ($)	Mar. 31, 2022 USD ($)	Sep. 14, 2022 USD ($)	Jan. 05, 2022 USD ($) tranche	Apr. 30, 2020 USD ($)	Feb. 29, 2016 USD ($)
Debt Instrument [Line Items]
Outstanding amount paid off					$ 81,750
Outstanding amount payoff					109,000
2027 Term Loans
Debt Instrument [Line Items]
Debt Instrument, Interest Rate During Period				13.03%
2027 Term Loans \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount							$ 300,000
Number of tranches \| tranche							4
Net carrying value				$ 245,718
Quarterly payments \| item			5
Loan agreement covenants, minimum trailing twelve month net sales for current quarter			$ 200,000	200,000
Loan agreement covenants, minimum trailing twelve month net sales for the quarter ended March 30, 2024			210,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended June 30, 2024			230,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended September 30, 2024			270,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended December 31, 2024 and thereafter			$ 300,000
Mandatory prepayment term			10 days
Debt discounts and issuance costs			$ 6,800
Remaining unamortized debt discount and debt offering costs				$ 4,282
2027 Term Loans \| Additional facility amount \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount			$ 100,000
2027 Term Loans \| Through March 31, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Stated interest rate			8.25%
2027 Term Loans \| Through March 31, 2023 \| BioPharma Credit Investments V GP LLC \| Three-month LIBOR
Debt Instrument [Line Items]
Floor On Variable Rate			1.00%
2027 Term Loans \| Starting April 1, 2023 \| Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Debt Instrument [Line Items]
Amount added to the variable component				0.26161%
Floor On Variable Rate				1.00%
2027 Term Loans \| Starting April 1, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Stated interest rate				8.25%
Tranche A Loan, funded January 5, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount							$ 100,000
Debt discounts and issuance costs			$ 7,800
Tranche B Loan, funded on March 31, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount		$ 100,000			100,000
Debt discounts and issuance costs					2,300
Convertible notes, Issuance Cost		$ 1,000			$ 1,000
Tranche C Loan, not funded between April 1, 2022 and March 17, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount			50,000
Tranche D Loan, funded on September 14, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount						$ 50,000
Convertible notes, Issuance Cost						$ 500
1.5% Convertible Senior Subordinated Notes due 2026 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount								$ 230,000
Net carrying value				$ 225,900
Stated interest rate								1.50%
Remaining unamortized debt discount and debt offering costs				$ 4,100
Effective interest rate				2.10%
1.5% Convertible Senior Subordinated Notes due 2026 \| BioPharma Credit Investments V GP LLC \| Scenario, Plan \| Minimum
Debt Instrument [Line Items]
Principal amount			50,000
8.2% Convertible Notes due 2022 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount			100,000						$ 100,000
Stated interest rate		8.20%			8.20%				8.20%
Outstanding amount payoff		$ 111,100	111,100
2025 Term Loan \| Lender
Debt Instrument [Line Items]
Principal amount	$ 75,000		75,000
Outstanding amount paid off			$ 81,900
Total term of the loan	6 years
Tranches A, B and D \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Remaining unamortized debt discount and debt offering costs				$ 4,300
Remaining term				3 years 9 months 18 days