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Collaborations and Other Arrangements (Details)
$ / shares in Units, $ in Thousands, € in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 16, 2021
USD ($)
$ / shares
shares
Mar. 23, 2021
USD ($)
Feb. 01, 2021
USD ($)
Nov. 04, 2019
EUR (€)
May 02, 2019
Mar. 31, 2022
USD ($)
Dec. 31, 2020
USD ($)
Oct. 31, 2018
USD ($)
item
Jan. 31, 2016
USD ($)
Mar. 31, 2025
USD ($)
Jun. 30, 2024
USD ($)
Dec. 31, 2023
USD ($)
$ / shares
Dec. 31, 2022
USD ($)
Dec. 31, 2022
EUR (€)
Dec. 31, 2021
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2019
EUR (€)
Apr. 14, 2020
$ / shares
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Research and development                       $ 109,436 $ 199,358   $ 363,105      
Share Price | $ / shares                       $ 3.33           $ 14.82
Upfront and milestone payment                       $ 25,000            
Royalties due                       38,400 2,900          
Vaccinex License Agreement                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Maximum aggregate milestone payments to be made   $ 3,500                                
Aggregate amount payable for achievement of certain regulatory milestones low single digit royalties on global net sales of any approved licensed products   $ 11,500                                
Bioeq IP AG                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Initial term of agreement       10 years                            
Percentage of gross profits shared       50.00% 50.00%                          
Bioeq IP AG | Licensed Products                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Maximum aggregate milestone payments | €       € 12.5                            
Additional milestone payments related to FDA approval | €                           € 2.5        
Bioeq IP AG | Research and development                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Upfront and milestone payment                               $ 11,100 € 10.0  
Adimab Development and Option Agreement                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Minimum antibodies to be commercialized under commercialization option | item               1                    
Technical milestone payments obligated to pay               $ 300                    
Period for payment of nominal research maintenance fee               4 years                    
Maximum aggregate milestone payments to be made               $ 13,000                    
Maximum antibodies partially exercised under commercialization option | item               10                    
Percentage of option fee to be paid on partial exercise of commercialization option               65.00%                    
Additional payment to be made               $ 0                    
Expiration term from the effective date without providing materials that pass quality control               12 months                    
Term of agreement               10 years                    
Novartis Agreement                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Term of agreement             10 years                      
Potential development milestones                 $ 325,000                  
Sales milestones                 $ 200,000                  
GSK Agreement                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Sales milestones             $ 485,000                      
Additional clinical milestones eligible to receive             60,000                      
Regulatory milestones eligible to receive             $ 155,000                      
GSK Agreement | Surface                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Milestone payments earned           $ 30,000                        
Junshi Biosciences                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
License Agreement Fee                       35,000            
Research and development                       8,000 68,500   $ 175,400      
Unregistered shares | shares 2,491,988                                  
Share Price | $ / shares $ 20.06                                  
Aggregate value $ 50,000                                  
Period before the company can sell, transfer or make any short sale of common stock (in years) 2 years                                  
Fair value for the discount for lack of marketability (DLOM)                       9,000            
Junshi Biosciences | Intangible assets, net and accrued and other current liabilities                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Accrued milestone payment                       25,000            
Junshi Biosciences | Accrued and other current liabilities                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Co-development, regulatory and technology transfer costs                       26,300 8,400          
Junshi Biosciences | Accounts payable                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Co-development, regulatory and technology transfer costs                       $ 6,300 $ 0          
Junshi Biosciences | Licensed Products                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Maximum paid amount for co-development activities (per licensed compound)     $ 25,000                              
Junshi Biosciences | Toripalimab (LOQTORZI)                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Collaboration Agreement, upfront amount paid     $ 150,000                              
Collaboration agreement, royalty on net sales, percentage     20.00%                              
Collaboration agreement, Maximum aggregate one-time payments for the achievement of various regulatory and sales milestones     $ 380,000                              
CHS-006 anti-TIGIT antibody                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
License Agreement Fee     $ 35,000     35,000                        
Collaboration agreement, royalty on net sales for each exercised option, percentage     18.00%                              
Collaboration agreement, Maximum aggregate one-time payment for achievement of milestones, for each option program     $ 85,000                              
CHS-006 anti-TIGIT antibody | Anti-TIGIT Antibody and IL-2 cytokine                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Collaboration Agreement , Maximum Payments On Attainment Of Certain Sales Thresholds For Each Option Program           $ 170,000                        
Scenario, Plan | Junshi Biosciences | Toripalimab (LOQTORZI) | Intangible assets, net and accrued and other current liabilities                                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions                                    
Upfront and milestone payment                   $ 12,500 $ 12,500