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Income Taxes (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Operating Loss Carryforwards [Line Items] |  |  |
Net deferred tax liabilities | $ 1,102 | $ 1,102 |
Increase and (decrease) Valuation allowance | (10,600) | 85,600 |
Unrecognized tax benefits | 19,247 | 17,417 | $ 16,838
Unrecognized tax benefits, accrued interest and penalties accrued | 0 | $ 0 | $ 0
Domestic Tax Jurisdiction |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Net operating loss carryforwards | $ 718,700 |  |
Net operating loss carryforwards expiration year | 2036 |  |
State and Local Jurisdiction |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Net operating loss carryforwards | $ 124,800 |  |
Net operating loss carryforwards expiration year | 2031 |  |
Federal research and development | Domestic Tax Jurisdiction |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carryforwards | $ 66,700 |  |
Tax credit carryforwards expiration year | 2031 |  |
Federal research and development | State and Local Jurisdiction |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carryforwards | $ 29,500 |  |

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