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Collaboration Agreements - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jun. 30, 2024 | Sep. 30, 2023 | Dec. 31, 2025 | Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Collaboration revenue |  |  | $ 8,995 | $ 0
Wellcome Leap Agreement |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Grant funds payment received |  | $ 3,300 |  |
Commercial research funding agreement termination date |  |  | May 31, 2024 |
Return of unused grant funds received | $ 2,400 |  |  |
Collaboration Agreement | Novartis Pharma AG |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Future long-term research, development, and commercial milestone payment |  |  | $ 530,000 |
Upfront payments and research funding |  |  | 20,000 |
Collaboration revenue |  |  | 9,000 | 0
Deferred revenue |  |  | 5,800 | 12,500
Deferred revenue current liabilities |  |  | 5,800 | $ 7,800
Collaboration Agreement | Novartis Pharma AG | Deferred Revenue |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Collaboration revenue |  |  | 6,700 |
Collaboration Agreement | Novartis Pharma AG | Reimbursable Costs |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Collaboration revenue |  |  | $ 2,200 |

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