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Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Summary of Stock Option Activity

The following table summarizes the stock option activity for the year ended December 31, 2025:

		Number of Options				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Life (Years)				Aggregate Intrinsic Value (in thousands)
Balance- December 31, 2024			5,384,142			$	9.61				7.8			$	1,022
Change in authorized shares			—
Granted			2,964,646				4.38
Exercised			(136,871	)			5.22
Forfeited/expired			(297,859	)			9.24
Balance- December 31, 2025			7,914,058			$	7.74				7.9			$	46,246
Vested and Exercisable- December 31, 2025			3,717,317			$	8.45				7.1			$	18,914

Summary of Estimated Fair Value of Stock Options Granted Weighted Average Assumptions

The weighted-average grant date fair value of stock options granted during the year ended December 31, 2025 and 2024 was $3.67 and $8.81, respectively, and were estimated on the date of grant using a Black-Scholes option pricing model with the following weighted-average assumptions:

		Year Ended December 31,
		2025				2024
Weighted-average risk-free interest rate			4.4	%			4.4	%
Expected term of stock options (in years)		6.0 years				6.0 years
Weighted-average expected stock price volatility			108.1	%			110.1	%
Estimated dividend yield			—				—

Schedule of Stock-based Compensation Expense

Stock-based compensation expense recorded as research and development and general and administrative expenses in the statements of operations and comprehensive loss is as follows (in thousands):

		Year Ended December 31,
		2025				2024
Research and development		$	3,188			$	1,939
General and administrative			8,503				5,040
Total stock-based compensation expense		$	11,691			$	6,979

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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