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Segment Reporting - Summary of Segment Net Loss, Including Significant Segment Expenses (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Segment Reporting Information [Line Items]    
Collaboration revenue $ 8,995 $ 0
Revenue from Contract with Customer, Product and Service [Extensible Enumeration] Collaborative Arrangement [Member] Collaborative Arrangement [Member]
Segment expenses:    
General and administrative $ 27,809 $ 19,158
Total operating expenses 101,775 78,194
Loss from operations (92,780) (78,194)
Total other income (expense), net 12,175 7,085
Net loss (80,605) (71,109)
Operating Segments    
Segment Reporting Information [Line Items]    
Collaboration revenue $ 8,995 $ 0
Revenue from Contract with Customer, Product and Service [Extensible Enumeration] Collaborative Arrangement [Member] Collaborative Arrangement [Member]
Segment expenses:    
Direct program costs $ 49,449 $ 37,132
Indirect research and development expenses 24,517 21,904
General and administrative 27,809 19,158
Total operating expenses 101,775 78,194
Loss from operations (92,780) (78,194)
Total other income (expense), net 12,175 7,085
Net loss $ (80,605) $ (71,109)