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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Net loss $ (54,117) $ (23,128)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 7,493 2,812
Noncash lease expense 897  
Foreign exchange remeasurement gain (454) (24)
Change in fair value of contingent consideration (346) 220
Depreciation and amortization 899 439
Other 276 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (2,825) 836
Other long-term assets (291) (2,216)
Accounts payable (3,199) (271)
Operating lease liabilities (456)  
Accrued expenses and current other liabilities (2,928) 3,603
Net cash used in operating activities (55,051) (17,729)
Cash flows from investing activities:    
Purchase of marketable securities (252,398) 0
Maturities of marketable securities 350,500 0
Purchases of property, plant and equipment (20,235) (9,129)
Net cash provided by (used in) investing activities 77,867 (9,129)
Cash flows from financing activities:    
Proceeds from initial public offering, net of issuance costs 0 340,876
Proceeds from issuance of convertible preferred stock, net of issuance costs 0 52,460
Proceeds from exercise of stock options 338 1,438
Other financing activities 0 (69)
Net cash provided by financing activities 338 394,705
Net increase in cash and cash equivalents 23,154 367,847
Effect of exchange rate changes on cash, cash equivalents and restricted cash 729 78
Cash, cash equivalents and restricted cash—beginning of period 38,090 241,764
Cash, cash equivalents and restricted cash—end of period 61,973 609,689
Supplemental disclosure of noncash information:    
Conversion of preferred stock to common stock upon IPO 0 384,426
Deferred offering costs in accrued expenses and other current liabilities 0 1,702
Purchases of property, plant and equipment in accounts payable and accrued expenses and other current liabilities $ 10,406 $ 862