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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash flows from operating activities: |  |
Net loss | $ (39,219) | $ (75,730)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 8,688 | 8,943
Non-cash lease expense | 165 | 115
Foreign exchange remeasurement loss (gain) | 162 | (723)
Impairment of fixed assets | 2,780 | 14,020
Impairment of right-of-use assets | 187 | 7,596
Change in fair value of contingent consideration | 196 | (81)
Depreciation | 1,968 | 2,767
Accretion on invested securities | (2,411) | (2,898)
Non-cash interest expense | 503 | 509
Change in fair value of derivative financial instrument | 888 | 120
Loss on disposals of property and equipment | 292 | 335
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 2,504 | (1,501)
Other long-term assets | (901) | (1,017)
Accounts payable | 11 | (227)
Operating lease liabilities | (634) | (539)
Accrued restructuring costs | (75) | (1,879)
Accrued expenses and other current liabilities | (108) | (4,032)
Net cash used in operating activities | (25,004) | (54,222)
Cash flows from investing activities: |  |
Purchase of marketable securities | (91,081) | (178,494)
Maturities of marketable securities | 111,700 | 218,800
Purchases of property, plant and equipment | 0 | (15,447)
Cash received from held for sale assets | 541 | 0
Net cash provided by investing activities | 21,160 | 24,859
Cash flows from financing activities: |  |
Proceeds from note payable | 0 | 8,669
Net cash provided by financing activities | 0 | 8,669
Net decrease in cash, cash equivalents and restricted cash | (3,844) | (20,694)
Effect of exchange rate changes on cash, cash equivalents and restricted cash | (71) | (97)
Cash, cash equivalents and restricted cash—beginning of period | 10,696 | 43,716
Cash, cash equivalents and restricted cash—end of period | 6,781 | 22,925
Supplemental disclosure of cash flow information: |  |
Cash paid for interest, net of amounts capitalized | 3,482 | 3,154
Supplemental disclosure of noncash information: |  |
Purchases of property, plant and equipment in accounts payable and accrued expenses and other current liabilities | $ 0 | $ 4,815

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