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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities:    
Net loss $ (62,240) $ (143,162)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 12,756 13,613
Non-cash lease expense 174 610
Foreign exchange remeasurement gain (278) (147)
Impairment of fixed assets 4,285 60,088
Impairment of right-of-use assets 827 7,724
Change in fair value of contingent consideration (2,500) (41)
Depreciation 2,869 3,720
In-process research and development expenses 10,000 0
Accretion on invested securities (3,861) (4,716)
Non-cash interest expense 754 762
Change in fair value of derivative financial instrument 265 528
Loss on disposals of property and equipment 343 338
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (4,033) (1,082)
Other long-term assets (3,115) 275
Accounts payable (34) (652)
Operating lease liabilities (995) (1,198)
Long term liabilities 0 (12)
Accrued expenses and other current liabilities (354) (5,296)
Net cash used in operating activities (45,137) (68,648)
Cash flows from investing activities:    
Purchase of marketable securities (106,684) (250,517)
Maturities of marketable securities 158,700 298,300
Purchases of property, plant and equipment 0 (20,605)
Cash received from held for sale assets 546 0
Acquired in-process research and development (10,000) 0
Purchase of derivative financial instrument (1,588) 0
Net cash provided by investing activities 40,974 27,178
Cash flows from financing activities:    
Principal payments on loan 0 (587)
Proceeds from exercise of stock options 159 0
Proceeds from note payable 0 8,669
Net cash provided by financing activities 159 8,082
Net decrease in cash, cash equivalents and restricted cash (4,004) (33,388)
Effect of exchange rate changes on cash, cash equivalents and restricted cash (29) (182)
Cash, cash equivalents and restricted cash—beginning of period 10,696 43,716
Cash, cash equivalents and restricted cash—end of period 6,663 10,146
Supplemental disclosure of cash flow information:    
Cash paid for interest, net of amounts capitalized 5,241 4,908
Supplemental disclosure of noncash information:    
Purchases of property, plant and equipment in accounts payable and accrued expenses and other current liabilities $ 0 $ 67