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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($) $ in Thousands | Total | Common Stock | Common Stock At Market Offering | Additional Paid-in Capital | Additional Paid-in Capital At Market Offering | Accumulated Other Comprehensive (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2023 |  | 6,503,913 |  |  |  |  |
Beginning balance at Dec. 31, 2023 | $ 225,829 | $ 0 |  | $ 807,158 |  | $ (348) | $ (580,981)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Stock-based compensation | 4,515 |  |  | 4,515 |  |  |
Net loss | (24,302) |  |  |  |  |  | (24,302)
Other comprehensive loss | (215) |  |  |  |  | (215) |
Ending balance (in shares) at Mar. 31, 2024 |  | 6,503,913 |  |  |  |  |
Ending balance at Mar. 31, 2024 | 205,827 | $ 0 |  | 811,673 |  | (563) | (605,283)
Beginning balance (in shares) at Dec. 31, 2023 |  | 6,503,913 |  |  |  |  |
Beginning balance at Dec. 31, 2023 | 225,829 | $ 0 |  | 807,158 |  | (348) | (580,981)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Net loss | (39,219) |  |  |  |  |  |
Ending balance (in shares) at Jun. 30, 2024 |  | 6,503,913 |  |  |  |  |
Ending balance at Jun. 30, 2024 | 195,019 | $ 0 |  | 815,846 |  | (627) | (620,200)
Beginning balance (in shares) at Mar. 31, 2024 |  | 6,503,913 |  |  |  |  |
Beginning balance at Mar. 31, 2024 | 205,827 | $ 0 |  | 811,673 |  | (563) | (605,283)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Stock-based compensation | 4,173 |  |  | 4,173 |  |  |
Net loss | (14,917) |  |  |  |  |  | (14,917)
Other comprehensive loss | (64) |  |  |  |  | (64) |
Ending balance (in shares) at Jun. 30, 2024 |  | 6,503,913 |  |  |  |  |
Ending balance at Jun. 30, 2024 | $ 195,019 | $ 0 |  | 815,846 |  | (627) | (620,200)
Beginning balance (in shares) at Dec. 31, 2024 | 6,525,887 | 6,525,887 |  |  |  |  |
Beginning balance at Dec. 31, 2024 | $ 169,436 | $ 0 |  | 824,780 |  | (228) | (655,116)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Issuance of common stock upon exercise of stock options (in shares) |  | 33,040,000 |  |  |  |  |
Issuance of common stock upon exercise of stock options | 404 |  |  | 404 |  |  |
Stock-based compensation | 3,495 |  |  | 3,495 |  |  |
Net loss | (28,200) |  |  |  |  |  | (28,200)
Other comprehensive loss | (223) |  |  |  |  | (223) |
Ending balance (in shares) at Mar. 31, 2025 |  | 6,558,927 |  |  |  |  |
Ending balance at Mar. 31, 2025 | $ 144,912 | $ 0 |  | 828,679 |  | (451) | (683,316)
Beginning balance (in shares) at Dec. 31, 2024 | 6,525,887 | 6,525,887 |  |  |  |  |
Beginning balance at Dec. 31, 2024 | $ 169,436 | $ 0 |  | 824,780 |  | (228) | (655,116)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Net loss | $ (49,594) |  |  |  |  |  |
Ending balance (in shares) at Jun. 30, 2025 | 6,750,716 | 6,750,716 |  |  |  |  |
Ending balance at Jun. 30, 2025 | $ 131,670 | $ 0 |  | 837,185 |  | (805) | (704,710)
Beginning balance (in shares) at Mar. 31, 2025 |  | 6,558,927 |  |  |  |  |
Beginning balance at Mar. 31, 2025 | 144,912 | $ 0 |  | 828,679 |  | (451) | (683,316)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Issuance of common stock upon exercise of stock options (in shares) |  | 5,952 |  |  |  |  |
Issuance of common stock upon exercise of stock options | 71 |  |  | 71 |  |  |
Issuance of common stock in at-the-market offering, net of $0.3 million in issuance costs (in shares) |  |  | 185,837 |  |  |  |
Issuance of common stock in at-the-market offering, net of $0.3 million in issuance costs | 6,611 |  |  |  | $ 6,611 |  |
Stock-based compensation | 1,824 |  |  | 1,824 |  |  |
Net loss | (21,394) |  |  |  |  |  | (21,394)
Other comprehensive loss | $ (354) |  |  |  |  | (354) |
Ending balance (in shares) at Jun. 30, 2025 | 6,750,716 | 6,750,716 |  |  |  |  |
Ending balance at Jun. 30, 2025 | $ 131,670 | $ 0 |  | $ 837,185 |  | $ (805) | $ (704,710)

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