    <SEC-DOCUMENT>0001193125-23-074011-index.html : 20230317
    <SEC-HEADER>0001193125-23-074011.hdr.sgml : 20230317
    <ACCEPTANCE-DATETIME>20230317165312
    ACCESSION NUMBER:		0001193125-23-074011
    CONFORMED SUBMISSION TYPE:	424B3
    PUBLIC DOCUMENT COUNT:		17
    FILED AS OF DATE:		20230317
    DATE AS OF CHANGE:		20230317

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Scilex Holding Co
    		CENTRAL INDEX KEY:			0001820190
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B3
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-268607
    		FILM NUMBER:		23743453

    	BUSINESS ADDRESS:
    		STREET 1:		960 SAN ANTONIO ROAD
    		CITY:			PALO ALTO
    		STATE:			CA
    		ZIP:			94303
    		BUSINESS PHONE:		(650) 516-4310

    	MAIL ADDRESS:
    		STREET 1:		960 SAN ANTONIO ROAD
    		CITY:			PALO ALTO
    		STATE:			CA
    		ZIP:			94303

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Scilex Holding Company/DE
    		DATE OF NAME CHANGE:	20221117

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Vickers Vantage Corp. I
    		DATE OF NAME CHANGE:	20200804
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B3
    <SEQUENCE>1
    <FILENAME>d418853d424b3.htm
    <DESCRIPTION>424B3
    <TEXT>
    Document 1 - file: d418853d424b3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g418853g00a01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g418853g00a01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g418853g00a03.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g418853g00a03.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g418853g00a04.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g418853g00a04.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g418853g00a05.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g418853g00a05.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g418853g00a06.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g418853g00a06.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g418853g00a08.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g418853g00a08.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g418853g00a09.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g418853g00a09.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g418853g00a10.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g418853g00a10.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g418853g00a11.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g418853g00a11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g418853g00a13.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g418853g00a13.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g418853g00a14.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g418853g00a14.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>g418853g00a15.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: g418853g00a15.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>g418853g00a16.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: g418853g00a16.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>g418853g00a17.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: g418853g00a17.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>g418853g00a18.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: g418853g00a18.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>g418853g11q22.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: g418853g11q22.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>