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v3.25.2

Fair Value Measurements (Additional Information) (Details) - USD ($) |  |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | ---
Jun. 30, 2024 | Sep. 30, 2023 | Apr. 30, 2023 | Oct. 31, 2024 | Sep. 30, 2023 | Mar. 31, 2025 | Mar. 31, 2024 | Dec. 31, 2024 | Dec. 31, 2023 | Oct. 08, 2024
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Note discount rate |  |  |  |  |  | 12907.00% |  | 128.82% | 13.05% |
Principle amount of issued debt |  |  | $ 25,000,000 |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  |  |  | 5,467,692 | 6,854,309 |
Derivative warrant liabilities |  |  |  |  |  | $ 7,900,000 |  | $ 18,300,000 |  |
Accumulated other comprehensive income |  |  |  |  |  | 6,317,000 |  | 6,317,000 | $ 0 |
Purchased revenue liability |  |  |  |  |  | 7,300,000 |  | 6,800,000 |  | $ 5,900,000
(Gain) loss on derivative liability |  |  |  |  |  | 10,409,000 | $ (457,000) | 17,378,000 | (512,000) |
Common stock upon conversation of cash |  |  |  |  |  | $ 3,000,000 |  | $ 3,000,000 |  |
Discount rate of FDA |  |  |  |  |  | 9.60% |  | 10.00% |  |
Development Milestone Payment |  |  |  |  |  | $ 200,000 |  | $ 200,000 | 200,000 |
Warrants |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 5,467,692 |  | 156,220 |  |
(Gain) loss on derivative liability |  |  |  |  |  | $ 10,400 | 500,000 | $ 17,400,000 | (500,000) |
Convertible Debentures |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
(Gain) loss on derivative liability |  |  |  |  |  |  |  | 35,000 | 4,400,000 |
Oramed Note |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Estimated fair value |  |  |  |  |  | 15,000,000 |  | 12,200,000 | 104,100,000 |
Principle amount of issued debt | $ 10,000,000 | $ 101,900,000 |  |  | $ 101,900,000 |  |  |  |  |
Accumulated other comprehensive income |  |  |  |  |  |  |  | 5,000,000 |  |
Change in fair value of debt and liability instruments |  |  |  |  |  | 2,800,000 | $ 3,800,000 | 3,600,000 | 2,800,000 |
Change in fair value due to credit risk |  |  |  |  |  |  |  | 6,300,000 | $ 0 |
Tranche BNotes Member |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Estimated fair value |  |  |  |  |  | 24,500,000 |  | 23,600,000 |  |
Principle amount of issued debt |  |  |  | $ 50,000,000 |  |  |  |  |  |
Change in fair value of debt and liability instruments |  |  |  |  |  | 2,500,000 |  | 6,600,000 |  |
Purchased Revenue Liability |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Change in fair value of debt and liability instruments |  |  |  |  |  | 800,000 |  | 900,000 |  |
FSF Deposit Member |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Change in fair value of debt and liability instruments |  |  |  |  |  |  |  | 4,700,000 |  |
Gloperba Elyxyb Royalty Purchase Agreement |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Purchased revenue liability |  |  |  |  |  | $ 7,300,000 |  | $ 6,800,000 |  |
Private Placement |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 1,000,000 |  | 1,000,000 |  |
Private Placement | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 28,572 |  | 28,572 |  |
February 2024 BDO Firm Warrants [Member] |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 3,803,447 |  | 3,803,447 |  |
February 2024 BDO Firm Warrants [Member] | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 108,686 |  | 108,686 |  |
April 2024 RDO Common Warrants [Member] |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 15,000,000 |  | 15,000,000 |  |
April 2024 RDO Common Warrants [Member] | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 428,572 |  | 428,572 |  |
Deposit Warrants |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 3,250,000 |  | 3,250,000 |  |
Deposit Warrants | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 3,250,000 |  | 3,250,000 |  |
October 2024 Noteholder Warrants |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 7,500,000 |  | 7,500,000 |  |
October 2024 Noteholder Warrants | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 214,284 |  | 214,284 |  |
December 2024 RDO Common Warrants |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 57,512,958 |  | 57,512,958 |  |
December 2024 RDO Common Warrants | Common Stock |  |  |  |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants outstanding |  |  |  |  |  | 1,642,871 |  | 1,642,871 |  |

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