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Cover Page
 3 Months Ended
Mar. 31, 2025
Document Information [Line Items]  
Document Type S-1
Amendment Flag false
Entity Central Index Key 0001820190
Entity Tax Identification Number 92-1062542
Entity Registrant Name Scilex Holding Company
Entity Incorporation, State or Country Code DE
Entity Address, Address Line One 960 San Antonio Road
Entity Address, City or Town Palo Alto
Entity Address, State or Province CA
Entity Address, Postal Zip Code 94303
City Area Code 650
Local Phone Number 516-4310
Entity Filer Category Non-accelerated Filer
Entity Small Business true
Entity Emerging Growth Company true
Entity Ex Transition Period true
Entity Primary SIC Number 2836
Business Contact [Member]  
Document Information [Line Items]  
Entity Address, Address Line One 960 San Antonio Road
Entity Address, City or Town Palo Alto
Entity Address, State or Province CA
Entity Address, Postal Zip Code 94303
City Area Code 650
Local Phone Number 516-4310