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Significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2022
Significant accounting policies  
Schedule of estimated useful lives of property and equipment
        –     Properties leased for own use    Over the unexpired lease period
  –     Office equipment leased for own use    Over the unexpired lease period
  –     Leasehold improvements    Shorter period of the lease term or the useful life
  –     Fixtures and furniture    3 - 5 years
  –     Office and lab equipment    3 - 5 years
  –     Computer equipment    3 years
  –     Motor vehicles    3 - 5 years
  –     Manufacturing equipment    3 - 5 years
Schedule of estimated useful lives of intangible assets
–   Website and mobile apps
   2 years
–   Trademark and technology
   10 - 20 years
–   Products development cost
   3 years
–   Computer software
   3 years
–   Customer relationship
   10 years