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Commitments and Contingencies (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024 | Dec. 31, 2025 | Jan. 31, 2016
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Research and development | $ 5,039 | $ 7,208 | $ 19,823 | $ 22,947 |  |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Royalty expense |  |  | 0 |  |  |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | University |  |  |  |  |  |
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Research and development |  |  | $ 0 | $ 400 |  |
Aggregate sales milestone payments per product |  |  |  |  |  | $ 20,900
Minimum |  |  |  |  |  |
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Royalty rates (as a percent) |  |  | 0.25% |  |  |
Maximum |  |  |  |  |  |
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Royalty rates (as a percent) |  |  | 2.00% |  |  |
Forecast | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | University |  |  |  |  |  |
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |
Future minimum annual maintenance payments |  |  |  |  | $ 100 |

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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 220 -SubTopic 40 -Name Accounting Standards Codification -Section 55 -Paragraph 18 -Publisher FASB -URI https://asc.fasb.org/1943274/2147476153/220-40-55-18 Reference 2: http://www.xbrl.org/2003/role/exampleRef -Topic 220 -SubTopic 40 -Name Accounting Standards Codification -Section 55 -Paragraph 14 -Publisher FASB -URI https://asc.fasb.org/1943274/2147476153/220-40-55-14 Reference 3: http://www.xbrl.org/2003/role/exampleRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 55 -Paragraph 48 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482785/280-10-55-48 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 985 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481283/985-20-50-2 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Topic 730 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482916/730-10-50-1 Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 912 -SubTopic 730 -Name Accounting Standards Codification -Section 25 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479532/912-730-25-1 + Details
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