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v3.25.3

Segment Reporting (Details) $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2025 USD ($) | Jun. 30, 2025 USD ($) | Mar. 31, 2025 USD ($) | Sep. 30, 2024 USD ($) | Jun. 30, 2024 USD ($) | Mar. 31, 2024 USD ($) | Sep. 30, 2025 USD ($) entity | Sep. 30, 2024 USD ($) | Dec. 31, 2024 USD ($)
Segment Reporting [Abstract] |  |  |  |  |  |  |  |  |
Number of reportable segments | entity |  |  |  |  |  |  | 1 |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Research and development | $ 5,039 |  |  | $ 7,208 |  |  | $ 19,823 | $ 22,947 |
Employee related general and administrative expenses | 3,006 |  |  | 3,136 |  |  | 9,049 | 8,563 |
Net loss | (10,083) | $ (10,561) | $ (11,209) | (18,838) | $ (7,229) | $ (11,827) | (31,853) | (37,894) |
Total segment assets | 28,284 |  |  |  |  |  | 28,284 |  | $ 28,178
Reportable Segment |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Contract and grant reimbursements | 0 |  |  | (544) |  |  | (754) | (888) |
Employee related general and administrative expenses | 1,333 |  |  | 846 |  |  | 3,782 | 2,724 |
Professional fees and other general and administrative expenses | 1,670 |  |  | 2,289 |  |  | 5,259 | 5,837 |
Other segment items | 2,039 |  |  | 8,496 |  |  | 2,984 | 6,387 |
Net loss | 10,083 |  |  | 18,838 |  |  | 31,853 | 37,894 |
Total segment assets | 28,284 |  |  |  |  |  | 28,284 |  | $ 28,178
Clinical trial expenses | Reportable Segment |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Research and development | 1,054 |  |  | 3,757 |  |  | 8,491 | 9,304 |
Employee related research and development expenses | Reportable Segment |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Research and development | 2,073 |  |  | 1,995 |  |  | 6,696 | 6,147 |
Chemistry, manufacturing and controls expenses | Reportable Segment |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Research and development | 456 |  |  | 476 |  |  | 1,486 | 3,534 |
Other research and development expenses | Reportable Segment |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Research and development | $ 1,458 |  |  | $ 1,523 |  |  | $ 3,909 | $ 4,849 |

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