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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash flows from operating activities |  |
Net loss | $ (70,522) | $ (92,182)
Adjustments to reconcile net loss to net cash used in operating activities |  |
Depreciation | 135 | 65
Loss on disposal of fixed assets | 100 |
Gain on lease termination | (88) |
Amortization of right-of-use assets - operating | 589 | 208
Stock-based compensation | 12,314 | 14,435
Accretion of marketable securities, net | (4,793) | (4,569)
Changes in operating assets and liabilities |  |
Prepaid expenses and other assets | (5,391) | (1,515)
Operating lease liabilities | (377) | (197)
Accounts payable | 828 | (2,371)
Accrued expenses | (4,958) | 5,923
Net cash used in operating activities | (72,163) | (80,203)
Cash flows from investing activities |  |
Purchases of marketable securities, available-for-sale | (176,160) | (172,821)
Proceeds from maturities of marketable securities, available-for-sale | 142,640 | 189,000
Purchases of property and equipment | (235) | (255)
Net cash (used in) provided by investing activities | (33,755) | 15,924
Cash flows from financing activities |  |
Proceeds from issuance of common stock from private placement, net of offering costs | 95,046 |
Proceeds from issuance of common stock from at-the-market offering,net of commissions and offering expenses |  | 48,408
Proceeds from exercise of stock options | 118 | 2,570
Proceeds from issuance of common stock under employee stock purchase plan | 114 | 214
Deferred offering costs |  | (73)
Net cash provided by financing activities | 95,278 | 51,119
Effect of exchange rates on cash, cash equivalents and restricted cash | (14) | 58
Net decrease in cash, cash equivalents and restricted cash | (10,654) | (13,102)
Cash, cash equivalents and restricted cash, beginning of period | 52,554 | 64,819
Cash, cash equivalents and restricted cash, end of period | $ 41,900 | 51,717
Supplemental disclosure for investing and financing non-cash activities: |  |
Purchases of property and equipment included in accounts payable and accrued expenses |  | 30
Exercise of stock options |  | 54
Unpaid deferred offering costs |  | $ 66

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