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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands | Total | Series A Non-Voting Convertible Preferred Stock | Common Stock | Additional Paid-in Capital | Accumulated Other Comprehensive Loss | Accumulated Deficit
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2022 | $ 353,895 |  | $ 6 | $ 581,237 | $ (1,123) | $ (226,225)
Balance, shares at Dec. 31, 2022 |  |  | 56,980,845 |  |  |
Issuance of common stock from at-the-market offering, net of commissions and offering expenses | 48,408 |  |  | 48,408 |  |
Issuance of common stock from at-the-market offering, net of commissions and offering expenses, shares |  |  | 1,176,470 |  |  |
Issuance of common stock upon exercise of stock options | 4,273 |  |  | 4,273 |  |
Issuance of common stock upon exercise of stock options, shares |  |  | 770,934 |  |  |
Issuance of common stock upon vesting of restricted common stock, shares |  |  | 33,917 |  |  |
Shares issued under employee stock purchase plan | 214 |  |  | 214 |  |
Shares issued under employee stock purchase plan, shares |  |  | 9,765 |  |  |
Stock-based compensation expense | 22,443 |  |  | 22,443 |  |
Unrealized gain on marketable securities | 544 |  |  |  | 544 |
Foreign currency translation | 72 |  |  |  | 72 |
Net loss | (146,209) |  |  |  |  | (146,209)
Balance at Sep. 30, 2023 | 283,640 |  | $ 6 | 656,575 | (507) | (372,434)
Balance, shares at Sep. 30, 2023 |  |  | 58,971,931 |  |  |
Balance at Dec. 31, 2022 | 353,895 |  | $ 6 | 581,237 | (1,123) | (226,225)
Balance, shares at Dec. 31, 2022 |  |  | 56,980,845 |  |  |
Balance at Dec. 31, 2023 | 243,923 |  | $ 6 | 663,154 | (50) | (419,187)
Balance, shares at Dec. 31, 2023 |  |  | 59,239,113 |  |  |
Balance at Jun. 30, 2023 | 327,807 |  | $ 6 | 646,918 | (710) | (318,407)
Balance, shares at Jun. 30, 2023 |  |  | 58,713,982 |  |  |
Issuance of common stock upon exercise of stock options | 1,649 |  |  | 1,649 |  |
Issuance of common stock upon exercise of stock options, shares |  |  | 249,257 |  |  |
Issuance of common stock upon vesting of restricted common stock, shares |  |  | 8,692 |  |  |
Stock-based compensation expense | 8,008 |  |  | 8,008 |  |
Unrealized gain on marketable securities | 192 |  |  |  | 192 |
Foreign currency translation | 11 |  |  |  | 11 |
Net loss | (54,027) |  |  |  |  | (54,027)
Balance at Sep. 30, 2023 | 283,640 |  | $ 6 | 656,575 | (507) | (372,434)
Balance, shares at Sep. 30, 2023 |  |  | 58,971,931 |  |  |
Balance at Dec. 31, 2023 | 243,923 |  | $ 6 | 663,154 | (50) | (419,187)
Balance, shares at Dec. 31, 2023 |  |  | 59,239,113 |  |  |
Issuance of preferred stock from private placement, net of issuance costs | 26,642 |  |  | 26,642 |  |
Issuance of preferred stock from private placement, net of issuance costs, shares |  | 70,601 |  |  |  |
Issuance of common stock from private placement, net of issuance costs | 95,046 |  | $ 1 | 95,045 |  |
Issuance of common stock from private placement, net of issuance costs, shares |  |  | 11,174,000 |  |  |
Issuance of common stock upon exercise of stock options | $ 130 |  |  | 130 |  |
Issuance of common stock upon exercise of stock options, shares | 133,571 |  | 133,571 |  |  |
Issuance of common stock upon vesting of restricted common stock, shares |  |  | 65,544 |  |  |
Shares issued under employee stock purchase plan | $ 114 |  |  | 114 |  |
Shares issued under employee stock purchase plan, shares |  |  | 56,903 |  |  |
Stock-based compensation expense | 17,765 |  |  | 17,765 |  |
Unrealized gain on marketable securities | 741 |  |  |  | 741 |
Foreign currency translation | 182 |  |  |  | 182 |
Net loss | (105,771) |  |  |  |  | (105,771)
Balance at Sep. 30, 2024 | 278,772 |  | $ 7 | 802,850 | 873 | (524,958)
Balance, shares at Sep. 30, 2024 |  | 70,601 | 70,669,131 |  |  |
Balance at Jun. 30, 2024 | 280,795 |  | $ 7 | 770,745 | (248) | (489,709)
Balance, shares at Jun. 30, 2024 |  |  | 70,662,806 |  |  |
Issuance of preferred stock from private placement, net of issuance costs | 26,642 |  |  | 26,642 |  |
Issuance of preferred stock from private placement, net of issuance costs, shares |  | 70,601 |  |  |  |
Issuance of common stock upon exercise of stock options | 12 |  |  | 12 |  |
Issuance of common stock upon exercise of stock options, shares |  |  | 5,575 |  |  |
Issuance of common stock upon vesting of restricted common stock, shares |  |  | 750 |  |  |
Stock-based compensation expense | 5,451 |  |  | 5,451 |  |
Unrealized gain on marketable securities | 922 |  |  |  | 922 |
Foreign currency translation | 199 |  |  |  | 199 |
Net loss | (35,249) |  |  |  |  | (35,249)
Balance at Sep. 30, 2024 | $ 278,772 |  | $ 7 | $ 802,850 | $ 873 | $ (524,958)
Balance, shares at Sep. 30, 2024 |  | 70,601 | 70,669,131 |  |  |

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