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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities    
Net loss $ (105,771) $ (146,209)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation 201 98
Loss on disposal of fixed assets 100  
Gain on lease termination (88)  
Loss on impairment   285
Amortization of operating lease right-of-use assets 832 440
Stock-based compensation 17,765 22,443
Accretion of marketable securities, net (7,404) (6,989)
Changes in operating assets and liabilities    
Prepaid expenses and other assets (2,474) 5,679
Operating lease liabilities (607) (234)
Accounts payable (3,468) 2,839
Accrued expenses (6,710) 6,781
Net cash used in operating activities (107,624) (114,867)
Cash flows from investing activities    
Purchases of marketable securities, available-for-sale (208,413) (243,607)
Proceeds from maturities of marketable securities, available-for-sale 204,140 298,725
Purchases of property and equipment (235) (303)
Net cash (used in) provided by investing activities (4,508) 54,815
Cash flows from financing activities    
Proceeds from issuance of common stock from private placement, net of offering costs 95,046  
Proceeds from issuance of Series A non-voting convertible preferred stock from private placement, net of offering costs 26,850  
Proceeds from issuance of common stock from at-the-market offering,net of commissions and offering expenses   48,408
Proceeds from exercise of stock options 130 4,273
Proceeds from issuance of common stock under employee stock purchase plan 114 214
Deferred offering costs   (151)
Net cash provided by financing activities 122,140 52,744
Effect of exchange rates on cash, cash equivalents and restricted cash 178 74
Net increase (decrease) in cash, cash equivalents and restricted cash 10,186 (7,234)
Cash, cash equivalents and restricted cash, beginning of period 52,554 64,819
Cash, cash equivalents and restricted cash, end of period 62,740 57,585
Supplemental disclosure for investing and financing non-cash activities:    
Purchases of property and equipment included in accounts payable and accrued expenses   103
Unpaid deferred offering costs   $ 59
Unpaid costs associated with the issuance of Series A non-voting convertible preferred stock from private placement $ 208