
<PAGE>
 
   As filed with the Securities and Exchange Commission on December 21, 1995
                                                   Registration No. 33-_________
================================================================================
                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                                    FORM S-8
                             REGISTRATION STATEMENT
                                     Under
                           THE SECURITIES ACT OF 1933

                 BUSINESS RECORDS CORPORATION HOLDING COMPANY
              (Exact name of registrant as specified in charter)

                 Delaware                              75-1533071
        (State of incorporation)          (I.R.S. Employer Identification No.)

  1111 W. Mockingbird Lane, Suite 1400
              Dallas, Texas                               75247
(Address of principal executive offices)               (Zip Code)

               CLINICAL RESOURCE SYSTEMS, INC. STOCK OPTION PLAN
         CLINICAL RESOURCE SYSTEMS, INC. COMMON STOCK PURCHASE WARRANT
                            EXPIRING AUGUST 9, 1996
                           (Full title of the plans)

                                                     (With Copy To)
            Thomas E. Kiraly                      Jeffrey M. Sone, Esq.
  1111 W. Mockingbird Lane, Suite 1400     Arter, Hadden, Johnson & Bromberg
            Dallas, TX  75247                 1717 Main Street, Suite 4100
 (Name and address of agent for service)         Dallas, TX  75201-4605

  Telephone number, including area code, of agent for service:  (214) 688-1800

                        CALCULATION OF REGISTRATION FEE
<TABLE>
<CAPTION>
===============================================================================================
                                                    Proposed        Proposed
                                                     maximum         maximum
                                     Amount         offering        aggregate        Amount of
Title of securities                   to be           price         offering       registration
to be registered                   registered       per share      price(2)(3)        fee(3)
- -----------------------------------------------------------------------------------------------
<S>                                <C>              <C>            <C>             <C>
Common Stock, $.10 par value         14,381(1)        (2)(3)        $508,742         $175.43
===============================================================================================
</TABLE>

(1)  The securities to be registered represent (i) 13,933 shares of Common Stock
     issuable under the CRS Stock Option Plan and (ii) 448 shares of Common
     Stock issuable upon the exercise of that Clinical Resource Systems, Inc.
     Common Stock Purchase Warrant Expiring August 9, 1996.
(2)  Estimated solely for the purpose of calculating the registration fee.
(3)  Calculated pursuant to Rule 457(h) under the Securities Act of 1933, as
     amended:  the maximum proposed offering price at which outstanding options
     under the Clinical Resource Systems, Inc. Stock Option Plan and Clinical
     Resource Systems, Inc. Common Stock Purchase Warrant Expiring August 9,
     1996 may be exercised is $508,742 (14,381 shares of Common Stock).
<PAGE>
 
                                     PART I

              INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS

ITEM 1.  PLAN INFORMATION

          Under the Clinical Resource Systems, Inc. Stock Option Plan, effective
March 31, 1989 (the "CRS Option Plan"), Clinical Resource Systems, Inc., a Texas
corporation ("CRS"), was authorized to issue options to purchase an aggregate of
up to 600,000 shares of CRS Common Stock, $0.002 par value per share (the "CRS
Common Stock"), to officers and employees of CRS.  Pursuant to the terms of the
CRS Option Plan, in the event that CRS should be the surviving corporation in
any merger or consolidation, each outstanding stock option under the CRS Option
Plan was deemed to pertain and apply to the securities to which a holder of the
number of shares of CRS Common Stock subject to such stock option would have
been entitled as a result of such transaction.  Pursuant to the terms of that
certain Clinical Resource Systems, Inc. Common Stock Purchase Warrant expiring
August 9, 1996 (the "Warrant"), Dr. Robert G. McConnell, a director of CRS, was
entitled to purchase up to 66,670 shares of the CRS Common Stock upon the
exercise thereof.  Pursuant to the provisions of the Warrant, after a merger of
one or more corporations into CRS, the holder of the Warrant is entitled to
receive, in lieu of the shares of the CRS Common Stock, that number of shares of
stock or other securities or property to which such holder would have been
entitled pursuant to the terms of the agreement of merger or consolidation if,
immediately prior to such merger or consolidation, such holder had been the
holder of record of a number of shares of CRS Common Stock, equal to the number
and class of shares as to which the Warrant was then so exercisable.

          Pursuant to the terms of an Agreement and Plan of Merger, dated July
25, 1995, among the Registrant, BRC Merger Corp., CRS and certain individuals
(the "Merger Agreement"), BRC Merger Corp. was merged with and into CRS, CRS
became a wholly owned subsidiary of the Registrant and each issued and
outstanding share of the CRS Common Stock, was converted into the right to
receive .03366091 shares of the Common Stock, $0.10 par value per share, of the
Registrant.  Immediately prior to such merger, options to purchase 414,000
shares of the CRS Common Stock were outstanding under the CRS Option Plan and
the Warrant was exercisable as to 13,334 shares of the CRS Common Stock.
Pursuant to the terms of the CRS Option Plan and the Warrant, as a result of the
merger of BRC Merger Corp. with and into CRS, each of the individual holders of
options or the Warrant, as the case may be, set forth below became entitled to
receive, upon exercise of their respective options or Warrant, the number of
shares of the Common Stock, $0.10 par value per share, of the Registrant (the
"Company Common Stock") described opposite their name, in lieu of receiving the
number of shares of the CRS Common Stock also set forth opposite their name.
<TABLE>
<CAPTION>
                                                        NUMBER OF BUSINESS RECORDS
                          NUMBER OF CLINICAL RESOURCE       CORPORATION HOLDING
  NAME OF INDIVIDUAL         SYSTEMS, INC. SHARES             COMPANY SHARES
- -----------------------   ---------------------------   --------------------------
<S>                       <C>                           <C>
Andrew Galewsky                      200,000                       6,732
Daniel Galewsky                      100,000                       3,365
Phyllis Guillory                       2,000                          67
</TABLE>

                                      -2-
<PAGE>
 
<TABLE> 
<S>                       <C>                           <C>
Margot Clarke                          2,000                          67
Clyde Middleton, Jr.                  10,000                         336
Samuel E. Culotta                    100,000                       3,366
Robert G. McConnell                   13,334                         448
</TABLE>

          Accordingly, the securities registered hereby represent (i) 13,933
shares of Company Common Stock issuable by the Registrant under the CRS Option
Plan and (ii) 448 shares of Company Common Stock issuable by the Registrant upon
the exercise of the Warrant.

          The remainder of the information required by Part I to be contained in
the Section 10(a) prospectus is omitted from the Registration Statement in
accordance with Rule 428 under the Securities Act of 1933, as amended, and the
Note to Part I of Form S-8.

                  [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

                                      -3-
<PAGE>
 
                                    PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE.

          The following documents filed by Business Records Corporation Holding
Company (the "Registrant" or the "Company") with the Securities and Exchange
Commission are incorporated by reference in this registration statement:

          (1) Registrant's Annual Report on Form 10-K for the fiscal year ended
December 31, 1994 (the "1994 Form 10-K").

          (2) The Registrant's reports on Form 10-Q for the fiscal quarters
ended March 31, 1995, June 30, 1995 and September 30, 1995 as filed pursuant to
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
"Exchange Act") since the most recent fiscal year covered by the 1994 Form 10-K
described in (1) above.

          (3) The description of the Company's Common Stock contained in a
Registration Statement on Form 8-A, filed under the Exchange Act on February 16,
1988, Registration No. 0-8615, including any amendment or report filed for the
purpose of updating such description.

          In addition, all documents subsequently filed by the Company pursuant
to Section 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing
of a post-effective amendment which indicates that all securities offered have
been sold or which deregisters all securities then remaining unsold, shall be
deemed to be incorporated by reference in this registration statement and to be
a part hereof from the date of filing of such documents.

          Any statement contained herein or in a document incorporated or deemed
to be incorporated by reference herein shall be deemed to be modified or
superseded for purposes of this registration statement to the extent that the
statement contained herein or in any subsequently filed document which is deemed
to be incorporated by reference herein, or in any document forming any part of
the Section 10(a) Prospectus to be delivered to participants in connection with,
modifies or supersedes such statement.  Any such statement so modified or
superseded shall not be deemed, except as so modified or superseded, to
constitute a part of this registration statement.

ITEM 4.  DESCRIPTION OF SECURITIES.

          Not Applicable.

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

          Not Applicable.

                                     II-1
<PAGE>
 
ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

          Section 145 of the Delaware General Corporation Law empowers a
Delaware corporation, including the Company, to indemnify its directors,
officers, employees and agents under certain circumstances.  The Company's
Restated Bylaws ("Bylaws") provide that the Registrant shall indemnify such
persons to the full extent authorized or permitted by law.  The Bylaws further
provide that the Registrant may purchase and maintain liability insurance on
behalf of directors, officers, employees or agents of registrant, whether or not
registrant would have the power to indemnify them against such liability under
the provisions of law.  Moreover, the Company's Certificate of Incorporation, as
amended (the "Certificate"), provides that no director of registrant shall be
personally liable to registrant or its stockholders for breach of fiduciary duty
as a director to the fullest extent permitted by the Delaware General
Corporation Law.  The Delaware General Corporation Law prohibits such limitation
of liability for: (i) any breach of the duty of loyalty to registrant or its
stockholders, (ii) acts or omissions not in good faith or which involve
intentional misconduct or a knowing violation of law, (iii) liability under
Section 174 of the Delaware General Corporation Law (involving certain unlawful
dividends or stock repurchases), or (iv) any transaction from which the director
derived an improper personal benefit.

          The Registrant maintains an officers' and directors' liability
insurance policy insuring registrant's officers and directors against certain
liabilities and expenses incurred by them in their capacities as such, and
insuring registrant, under certain circumstances, in the event that
indemnification payments are made by registrant to such officers and directors.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED.

          Not Applicable.

ITEM 8.  EXHIBITS.

          See the Index to Exhibits following Part II this Registration
Statement.

ITEM 9.  UNDERTAKINGS.

     (a) The undersigned registrant hereby undertakes:

          (1) To file, during any period in which offers or sales are being
     made, a post-effective amendment to this registration statement:

               (i) To include any prospectus required by Section 10(a)(3) of the
          Securities Act of 1933;

               (ii) To reflect in the prospectus any facts or events arising
          after the effective date of the registration statement (or the most
          recent post-effective amendment thereof) which, individually or in the
          aggregate, represent a fundamental change in the information set forth
          in this registration statement;

                                     II-2
<PAGE>
 
               (iii) To include any material information with respect to the
          plan of distribution not previously disclosed in this registration
          statement or any material change to such information in this
          registration statement;

provided, however, that the undertaking set forth in paragraph (1)(i) and
(1)(ii) above do not apply if the information required to be included in a post-
effective amendment by those paragraphs is contained in periodic reports filed
with or furnished to the Commission by the registrant pursuant to Section 13 or
Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by
reference in this registration statement.

          (2) That, for the purpose of determining any liability under the
     Securities Act of 1933, each such post-effective amendment shall be deemed
     to be a new registration statement relating to the securities offered
     therein, and the offering of such securities at that time shall be deemed
     to be the initial bona fide offering thereof.

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

     (b) The undersigned registrant hereby further undertakes that, for purposes
of determining any liability under the Securities Act of 1933, each filing of
the registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Securities Exchange Act of 1934 (and, where applicable, each filing of the
annual report of the CRS Option Plan pursuant to Section 15(d) of the Securities
Exchange Act of 1934, if any) that is incorporated by reference in the
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

     (c) Insofar as indemnification for liabilities arising under the Securities
Act of 1933 may be permitted to directors, officers and controlling persons of
the registrant pursuant to the foregoing provisions, or otherwise, the
registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the Act
and is, therefore, unenforceable.  In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses
incurred or paid by a director, officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Act and will be governed by the final adjudication of
such issues.

                                     II-3
<PAGE>
 
                                  SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized in the City of Dallas and State of Texas on the 18 day of December,
1995.

                         BUSINESS RECORDS CORPORATION HOLDING COMPANY
                         (Registrant)

                         By:  /s/     Thomas E. Kiraly
                            -------------------------------------------------
                                      Thomas E. Kiraly
                                      Chief Financial Officer

                               POWER OF ATTORNEY

     Each of the undersigned hereby appoints Thomas E. Kiraly as attorney and
agent for the undersigned with full power of substitution, for and in the name,
place and stead of the undersigned, to sign and file with the Securities and
Exchange Commission under the Securities Act of 1933 any and all amendments and
exhibits to this Registration Statement and any and all applications,
instruments and other documents to be filed with the Securities and Exchange
Commission pertaining to the registration of the securities covered hereby, with
full power and authority to do and perform any and all acts and things
whatsoever requisite or desirable.

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons and in the
capacities indicated on December 18, 1995.
<TABLE>
<CAPTION>
     Signature                         Title
     ---------                         -----
<S>                                    <C>
/s/  P. E. Esping                      Chairman, Chief Executive Officer and
- ------------------------------------   Director (Principal Executive Officer)
     P. E. Esping                      

/s/  Thomas E. Kiraly                  Chief Financial Officer (Principal Financial Officer
- ------------------------------------   and Principal Accounting Officer)
     Thomas E. Kiraly 

/s/  L.D. Brinkman                     Director
- ------------------------------------ 
     L.D. Brinkman 

/s/  Robert E. Masterson               Director
- ------------------------------------ 
     Robert E. Masterson 

/s/  David H. Monnich                  Director
- ------------------------------------ 
     David H. Monnich 

/s/  Paul T. Stoffel                   Director
- ------------------------------------ 
     Paul T. Stoffel 
</TABLE>

                                     II-4
<PAGE>
 
                               INDEX TO EXHIBITS

<TABLE>
<CAPTION>
Exhibit
Number    Description of Document
- ------    -----------------------
<C>       <S>
4.1       Clinical Resource Systems, Inc. Stock Option Plan (filed herewith)

4.2       Form of Clinical Resource Systems, Inc. Stock Option Agreement (filed
          herewith)

4.3       Clinical Resource Systems, Inc. Common Stock Purchase Warrant
          Expiring August 9, 1996 (filed herewith)

4.4       Agreement and Plan of Merger, dated as of July 25, 1995, among
          Business Records Corporation Holding Company, BRC Merger Corp.,
          Clinical Resource Systems, Inc. and certain individuals (filed
          herewith)

5.1       Opinion of Arter, Hadden, Johnson & Bromberg (including their
          consent listed as Exhibit 24.1 to this Registration Statement) (filed
          herewith)

23.1      Consent of Arter, Hadden, Johnson & Bromberg (included in their
          opinion filed as Exhibit 5.1 to this Registration Statement)

23.2      Consent of Price Waterhouse LLP, independent accountants (filed
          herewith)

24.1      Power of Attorney (filed on the signature page, Page II-4 to this
          Registration Statement)
</TABLE>

                                     II-5
