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<SEC-DOCUMENT>0000950144-07-000647.txt : 20070130
<SEC-HEADER>0000950144-07-000647.hdr.sgml : 20070130
<ACCEPTANCE-DATETIME>20070130151804
ACCESSION NUMBER:		0000950144-07-000647
CONFORMED SUBMISSION TYPE:	DEF 14C
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20061214
FILED AS OF DATE:		20070130
DATE AS OF CHANGE:		20070130
EFFECTIVENESS DATE:		20070130

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ORTHODONTIX INC
		CENTRAL INDEX KEY:			0001006281
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MANAGEMENT SERVICES [8741]
		IRS NUMBER:				650643773
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14C
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-27836
		FILM NUMBER:		07564373

	BUSINESS ADDRESS:	
		STREET 1:		1428 BRICKELL AVENUE
		STREET 2:		SUITE 105
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131
		BUSINESS PHONE:		3054468661

	MAIL ADDRESS:	
		STREET 1:		1428 BRICKELL AVE
		STREET 2:		STE 105
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
		DATE OF NAME CHANGE:	19960124
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14C
<SEQUENCE>1
<FILENAME>g05044def14c.htm
<DESCRIPTION>ORTHODONTIX, INC.
<TEXT>
<HTML>
<HEAD>
<TITLE>Orthodontix, Inc.</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>
<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center" style="font-size: 14pt; margin-top: 12pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>Washington, D.C. 20549</B>
</DIV>

<DIV align="center" style="font-size: 18pt; margin-top: 12pt"><B>SCHEDULE 14C INFORMATION</B>
</DIV>


<DIV align="left" style="margin-left: 0%; text-indent: 0%; margin-right: 0%; font-size: 10pt; margin-top: 6pt">Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 (Amendment
No.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;)</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Check the appropriate box:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><FONT face="Wingdings">&#111;</FONT> Preliminary Information Statement<BR>
<FONT face="Wingdings">&#111;</FONT> Confidential, for Use of the Commission Only (as permitted by Rule&nbsp;14c-5(d)(2))<BR>
<FONT face="Wingdings">&#120;</FONT> Definitive Information Statement

</DIV>
<DIV align="center" style="font-size: 24pt; margin-top: 12pt"><B>ORTHODONTIX, INC.</B>
</DIV>

<DIV align="center" style="font-size: 10pt">(Name of Registrant As Specified in Charter)</DIV>



<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Payment of Filing Fee (Check the appropriate box):
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<FONT face="Wingdings">&#120;</FONT> No Fee required.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<FONT face="Wingdings">&#111;</FONT> Fee computed on table below per Exchange Act Rules&nbsp;14c-5(g) and 0 11.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1)&nbsp;Title of each class of securities to which transaction applies:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2)&nbsp;Aggregate number of securities to which transaction applies:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3)&nbsp;Per unit price or other underlying value of transaction computed pursuant to Exchange Act
Rule&nbsp;0-11 (set forth the amount on which the filing fee is calculated and state how it was
determined):
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) Proposed maximum aggregate value of transaction:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(5) Total fee paid:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<FONT face="Wingdings">&#111;</FONT> Fee paid previously with preliminary materials.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<FONT face="Wingdings">&#111;</FONT> Check box if any part of the fee is offset as provided by Exchange Act Rule&nbsp;0-11(a)(2)
and identify the filing for which the offsetting fee was paid previously. Identify the previous
filing by registration statement number, or the Form or Schedule and the date of its filing.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(1) Amount Previously Paid:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(2) Form, Schedule or Registration Statement No.:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(3) Filing Party:
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(4) Date Filed:
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">ORTHODONTIX, INC.
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">2 Snunit Street<BR>
Science Park<BR>
P.O.B 455<BR>
Carmiel, Israel 20100
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Dear Shareholders:
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We are writing to advise you that we intend to amend our Articles of Incorporation to change
our name to Protalix BioTherapeutics, Inc. and that we are terminating our 1998 Stock Option Plan
and adopting the 2006 Stock Incentive Plan. These actions were approved on December&nbsp;14, 2006 by
our Board of Directors. In addition, the holders of a majority of our issued and outstanding
voting securities also approved these actions on December&nbsp;14, 2006, by written consent in lieu of a
special meeting in accordance with the relevant sections of the Florida Business Corporation Act.
We will file the Articles of Amendment to our Articles of Incorporation, a copy of which is
attached hereto as Exhibit&nbsp;A, to change our name with the Secretary of State of Florida on or about
February&nbsp;20, 2007.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As described hereafter, these actions are required by the terms of our merger agreement (the
&#147;Merger Agreement&#148;) with Protalix Ltd., an Israeli biotechnology company, and Protalix Acquisition
Co., Ltd., an Israeli company that is our wholly-owned subsidiary and was formed to complete the
merger (the &#147;Merger&#148;).
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<B>WE ARE NOT ASKING YOU FOR A PROXY, AND YOU ARE REQUESTED NOT TO SEND US A PROXY.</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;No action is required by you. The accompanying Information Statement is furnished only to
inform our shareholders of the actions described above before they take place in accordance with
Rule&nbsp;14c-2 of the Securities Exchange Act of 1934. This Information Statement will be mailed to
you on or about February&nbsp;1, 2007.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Please feel free to call us at &#043;972 (4)&nbsp;988-9488 should you have any questions on the enclosed
Information Statement. We thank you for your continued interest in Orthodontix.
</DIV>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>
<TR>
    <TD valign="top" align="left">&nbsp;</TD>
    <TD colspan="3" align="left">For the Board of Directors of<BR>
Orthodontix, Inc.<BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ David Aviezer
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">David Aviezer, Ph.D.,&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">President and Chief Executive Officer&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>

</TABLE>

<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>

<DIV style="font-family: 'Times New Roman',Times,serif">


<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>

</TABLE>

<!-- TOC -->
<A name="toc"><DIV align="CENTER" style="page-break-before:always"><U><B>TABLE OF CONTENTS</B></U></DIV></A>

<P><CENTER>
<TABLE border="0" width="90%" cellpadding="0" cellspacing="0">
<TR>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="3%"></TD>
	<TD width="76%"></TD>
</TR>
<TR><TD colspan="9"><A HREF="#000">GENERAL</A></TD></TR>
<TR><TD colspan="9"><A HREF="#001">OUR PRINCIPAL SHAREHOLDERS</A></TD></TR>
<TR><TD colspan="9"><A HREF="#002">THE AMENDMENT</A></TD></TR>
<TR><TD colspan="9"><A HREF="#003">EMPLOYEE BENEFIT AND STOCK PLANS</A></TD></TR>
<TR><TD colspan="9"><A HREF="#004">WHERE YOU CAN OBTAIN ADDITIONAL INFORMATION</A></TD></TR>
</TABLE>
</CENTER>
<!-- /TOC -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>





<DIV align="center" style="font-size: 10pt; margin-top: 18pt">ORTHODONTIX, INC.<BR>
2 Snunit Street<BR>
Science Park<BR>
P.O.B. 455<BR>
Carmiel, Israel 20100<BR>
Telephone &#043;972 (4)&nbsp;988-9488
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">INFORMATION STATEMENT REGARDING<BR>
ACTION TO BE TAKEN BY WRITTEN CONSENT OF<BR>
MAJORITY SHAREHOLDERS<BR>
IN LIEU OF A SPECIAL MEETING
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>WE ARE NOT ASKING YOU FOR A PROXY,<BR>
AND YOU ARE REQUESTED NOT TO SEND US A PROXY.</B>
</DIV>

<!-- link1 "GENERAL" -->
<DIV align="left"><A NAME="000"></A></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">GENERAL
</DIV>



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This Information Statement is being furnished to the shareholders of Orthodontix, Inc., a
Florida corporation (the &#147;Company&#148;) in connection with the adoption of an Amendment to our Articles
of Incorporation by written consent of our Board of Directors and the holders of a majority of our
issued and outstanding voting securities in lieu of a special meeting. On December&nbsp;14, 2006, our
Board of Directors approved an amendment to our Articles of Incorporation to change our name to
Protalix BioTherapeutics, Inc. (the &#147;Amendment&#148;). This action will become effective on the date of
filing the Amendment with the Florida Secretary of State (the &#147;Effective Date of the Amendment&#148;) in
accordance with the written consent of our directors and the holders of a majority of our issued
and outstanding common stock and in accordance with the relevant sections of the Florida Business
Corporation Act.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;On December&nbsp;14, 2006, our Board of Directors also terminated our 1998 Stock Option Plan and
adopted the 2006 Stock Incentive Plan. This action was also approved by written consent on the
same date by the holders of a majority of our issued and outstanding voting securities. The terms
of the 2006 Stock Incentive Plan are similar to the terms of the stock option plan of Protalix
Ltd., the obligations of which we have assumed in connection with the
Merger. There are no stock options outstanding
under our 1998 Stock Option Plan, and we concluded that it would be preferable to adopt a new
incentive plan rather than to amend our 1998 Stock Option Plan.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;On December&nbsp;11, 2006 there were 5,830,856 shares of our common stock issued and outstanding.
The following shareholders who as of such date collectively owned approximately 57% of our
outstanding common stock, which was in excess of the required majority of outstanding voting
securities necessary for the adoption of this action at such time, have executed a written consent
approving the Amendment:
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="60%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">Shareholder</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000">No. of Shares Owned</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Frost Gamma Investments Trust</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">2,965,428</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Glenn L. Halpryn</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">380,100</TD>
    <TD>&nbsp;</TD>
</TR>
<TR style="font-size: 1px">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">TOTAL</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">3,345,528</TD>
    <TD>&nbsp;</TD>
</TR>
<TR style="font-size: 1px">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right" style="border-top: 3px double #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As
described hereafter, these actions were required by the terms of the Merger Agreement.
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The elimination of the need for a meeting of shareholders to approve this action is made
possible by Section&nbsp;607.0704 of the Florida Business Corporation Act, which provides that the
written consent of the holders of outstanding shares of voting stock, having not less than the
minimum number of votes that would be necessary to authorize or take such action at a meeting at
which all shares entitled to vote thereon were present and voted, may be substituted for such a
meeting. In order to eliminate the costs involved in holding a special meeting, our Board of
Directors voted to utilize the written consent of the holders of a majority in interest of our
voting securities.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our Board of Directors unanimously approved the reverse stock split and the merger. We did
not obtain, and we are not soliciting shareholder approval of these transactions. Florida law
allowed us to effect these transactions without obtaining or soliciting this approval. Florida law
does, however, require us to obtain approval from our shareholders to amend our Articles of
Incorporation to change our name to &#147;Protalix BioTherapeutics, Inc.&#148; In addition, applicable tax
law and SEC rules require us to obtain shareholder approval of our new 2006 Stock Incentive Plan.
Accordingly, we obtained the written consent of at least a majority of our shareholders approving
these actions and are mailing this information statement disclosing that we obtained this consent
to our remaining shareholders. In addition, the merger resulted in a change of a majority of our
directors and, accordingly, we have mailed an information statement disclosing this change to
our shareholders.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to Section&nbsp;607.0704 of the Florida Business Corporation Act, we are required to
provide prompt notice of the taking of the corporate action without a meeting of shareholders to
all shareholders who did not consent in writing to such action. This Information Statement serves
as this notice. This Information Statement will be mailed on or about February&nbsp;1, 2007 to
shareholders of record, and is being delivered to inform you of the corporate actions described
herein before they take effect in accordance with Rule&nbsp;14c-2 of the Securities Exchange Act of
1934.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The entire cost of furnishing this Information Statement will be borne by the Company. We
will request brokerage houses, nominees, custodians, fiduciaries and other like parties to forward
this Information Statement to the beneficial owners of our voting securities held of record by
them, and we will reimburse such persons for out-of-pocket expenses incurred in forwarding such
material.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">No Dissenter&#146;s Rights
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;No dissenter&#146;s rights are afforded to our shareholders under Florida law as a result of the
adoption of the Amendment.
</DIV>
<!-- link1 "OUR PRINCIPAL SHAREHOLDERS" -->
<DIV align="left"><A NAME="001"></A></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">OUR PRINCIPAL SHAREHOLDERS
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our voting securities are comprised of our common stock. The holders of our common stock are
entitled to one vote for each outstanding share on all matters submitted to our shareholders. The
following table contains information regarding record ownership of our common stock as of December
11, 2006 held by:
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->2<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always"><A HREF="#toc">Table of Contents</A></H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>persons who own beneficially more than 5% of our outstanding voting securities,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>our directors,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>named executive officers, and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>all of our directors and officers as a group.</TD>
</TR>

</TABLE>
</DIV>

<DIV align="left" style="margin-left: 0%; text-indent: 0%; margin-right: 0%; font-size: 10pt; margin-top: 6pt">The numbers do not give effect to the one-for-ten reverse stock split which went effective on
December&nbsp;29, 2006.</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="70%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="76%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left">Name and Address</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">Shares of Common Stock</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">Percent</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">of Beneficial Owner</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000">Beneficially Owned<SUP style="font-size: 85%; vertical-align: text-top">(1)</SUP></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000">Owned</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Phillip Frost, M.D.</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">2,965,428</TD>
    <TD nowrap>(2)</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">51.0 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">4400 Biscayne Blvd.</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33137</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Stephen Grussmark</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">450,000</TD>
    <TD nowrap>(3)</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">7.7 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">7400 North Kendall Drive Suite&nbsp;704</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33156</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Glenn L. Halpryn</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">380,100</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">6.5 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">1428 Brickell Avenue, Suite&nbsp;105</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33131</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Alan Jay Weisberg</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">4,201</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">0.07</TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">1428 Brickell Avenue, Suite&nbsp;105</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33131</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Noah Silver</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">0</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">0.0 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">1428 Brickell Avenue, Suite&nbsp;105</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33131</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Curtis Locksin</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">0</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">0.0 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">1428 Brickell Avenue, Suite&nbsp;105</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Miami, FL 33131
&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>

<TR><TD>&nbsp;</TD></TR>

<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">All Officers and</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">384,301</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right">&nbsp;</TD>
    <TD align="right">6.6 </TD>
    <TD nowrap>%</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Directors as a Group(2)</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Total Shares Outstanding
as of December&nbsp;11, 2006</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">5,830,856</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(1)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Beneficial ownership is determined in accordance with the rules of the Securities and
Exchange Commission. In computing the number of shares beneficially owned by a person and the
percentage ownership of that person, shares of common stock subject to options or warrants held by
that person that are currently exercisable or will become exercisable within 60&nbsp;days after December
11, 2006 are deemed outstanding, while such shares are not deemed outstanding for purposes of
computing percentage ownership of any other person. Unless otherwise indicated in the footnotes
below, the persons and entities named in the table have sole voting and investment power with
respect to all shares beneficially owned, subject to community property laws where applicable.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(2)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Represents shares of Common Stock held by Frost Gamma Investments Trust, of which Frost Gamma
Limited Partnership is the sole and exclusive beneficiary. Dr.&nbsp;Frost is the sole limited partner
of Frost Gamma, L.P. The general partner of Frost Gamma, L.P. is Frost Gamma, Inc. and the sole
shareholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr.&nbsp;Frost is also the sole
shareholder of Frost-Nevada Corporation.</TD>
</TR>

</TABLE>
</DIV>
<P align="center" style="font-size: 10pt"><!-- Folio -->3<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">(3)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Represents shares of Common Stock held in various trusts for which either Dr.&nbsp;Grussmark or his
wife is the sole trustee and the beneficiaries of which are Dr.&nbsp;Grussmark, his wife or his
children.</TD>
</TR>

</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Dr.&nbsp;Phillip Frost, a shareholder in Orthodontix, and Glenn L. Halpryn, the former
Chairman of our Board of Directors and a shareholder of Orthodontix, purchased stock in Protalix
Ltd. in September&nbsp;2006, along with other investors, to facilitate the Merger.
</DIV>
<!-- link1 "THE AMENDMENT" -->
<DIV align="left"><A NAME="002"></A></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">THE AMENDMENT
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;On December&nbsp;11, 2006, we had 5,830,856 shares of our common stock outstanding. At such time,
there were 1,500,000,000 shares of common stock authorized. There were also 100,000,000 shares of
preferred stock authorized, none of which have ever been issued. In connection with the Merger,
which was completed on December&nbsp;31, 2006, we effected a one-for-ten reverse stock split which
lowered our authorized capitalization to 150,000,000 shares of common stock and 10,000,000 shares
of preferred stock. In addition, we issued 61,198,679 shares of our common stock to former
shareholders of Protalix Ltd.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We originally incorporated as Embassy Acquisition Corp. in 1995 and changed our name to
Orthodontix, Inc. in April&nbsp;1998 when we entered the orthodontic practice management business. In
connection with the Merger, we agreed to change our name to Protalix BioTherapeutics, Inc., which
we believe will more accurately describe our business following the Merger and will preserve the
identity of our operating company, Protalix, Ltd.
</DIV>
<!-- link1 "EMPLOYEE BENEFIT AND STOCK PLANS" -->
<DIV align="left"><A NAME="003"></A></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">EMPLOYEE BENEFIT AND STOCK PLANS
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In connection with the Merger, we have reduced the number of our authorized shares and the
number of our issued and outstanding shares by effecting a one-for-ten reverse stock split. All
references to our common stock in the &#147;Employee Benefit and Stock Plans&#148; section of this
Information Statement give effect to the reverse split.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Immediately prior to the closing of the Merger, Protalix Ltd. had outstanding options to
purchase 88,001 ordinary shares under its employee stock option plan. Pursuant to the terms of the
Merger Agreement, we assumed all of the outstanding obligations under such plan and, accordingly,
we anticipate issuing 5,375,174 shares of our common stock upon the exercise of such options in
lieu of shares of Protalix Ltd.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our Board of Directors and a majority of our stockholders approved our 2006 Stock Incentive
Plan on December&nbsp;14, 2006. We have reserved 9,741,655 shares of our common stock for issuance, in
the aggregate, under the 2006 Stock Incentive Plan, subject to adjustment for a stock split, or any
future stock dividend or other similar change in our common stock or our capital structure. No
options to purchase shares of common stock have been granted under the 2006 Stock Incentive Plan;
however, we assumed options to purchase 5,413,249 shares
of our common stock under such plan in connection with the Merger.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">2006 Stock Incentive Plan
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our 2006 Stock Incentive Plan provides for the grant of stock options, restricted stock,
restricted stock units, stock appreciation rights and
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->4<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">dividend equivalent rights, collectively referred to as &#147;awards.&#148; Stock options granted under the
2006 Stock Incentive Plan may be either incentive stock options under the provisions of Section&nbsp;422
of the Internal Revenue Code, or non-qualified stock options. Incentive stock options may be
granted only to employees. Awards other than incentive stock options may be granted to employees,
directors and consultants. The 2006 Stock Incentive Plan is also in compliance with the provisions
of the Israeli Income Tax Ordinance &#091;New Version&#093;, 1961 (including as amended pursuant to Amendment
132 thereto) and is intended to enable us to grant awards to grantees who are Israeli residents as
follows: (i)&nbsp;awards to employees pursuant to Section&nbsp;102 of the Tax Ordinance (definition refers
only to employees, office holders and directors of our Company or a related entity excluding those
who are considered &#147;Controlling Shareholders&#148; pursuant to the Tax Ordinance); and (ii)&nbsp;awards to
non-employees pursuant to Section&nbsp;3(I) of the Tax Ordinance. In accordance with the terms and
conditions imposed by the Tax Ordinance, grantees who receive awards under the 2006 Stock Incentive
Plan may be afforded certain tax benefits in Israel as described below.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our Board of Directors or the compensation committee, referred to as the &#147;plan administrator,&#148;
will administer our 2006 Stock Incentive Plan, including selecting the grantees, determining the
number of shares to be subject to each award, determining the exercise or purchase price of each
award, and determining the vesting and exercise periods of each award.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The exercise price of stock options granted under the 2006 Stock Incentive Plan must be equal
to at least 100% of the fair market value of our common stock on the date of grant; however, in
certain circumstances, grants may be made at a lower price to Israeli grantees who are residents of
the State of Israel. If, however, incentive stock options are granted to an employee who owns
stock possessing more than 10% of the voting power of all classes of our stock or the stock of any
parent or subsidiary of our Company, the exercise price of any incentive stock option granted must
equal at least 110% of the fair market value on the grant date and the maximum term of these
incentive stock options must not exceed five years. The maximum term of all other awards must not
exceed 10&nbsp;years. The plan administrator will determine the exercise or purchase price (if any) of
all other awards granted under the 2006 Stock Incentive Plan.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under the 2006 Stock Incentive Plan, incentive stock options and options to Israeli grantees
may not be sold, pledged, assigned, hypothecated, transferred or disposed of in any manner other
than by will or by the laws of descent or distribution and may be exercised during the lifetime of
the participant only by the participant. Other awards shall be transferable by will or by the laws
of descent or distribution and to the extent and in the manner authorized by the plan administrator
by gift or pursuant to a domestic relations order to members of the participant&#146;s immediate family.
The 2006 Stock Incentive Plan permits the designation of beneficiaries by holders of awards,
including incentive stock options.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In the event the service of a participant in the 2006 Stock Incentive Plan is terminated for
any reason other than cause, disability or death, the participant may exercise awards that were
vested as of the termination date for a period ending upon the earlier of 12&nbsp;months or the
expiration date of the awards unless otherwise determined by the plan administrator.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In the event of a corporate transaction or a change of control, all awards will terminate
unless assumed by the successor corporation. Unless
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->5<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">otherwise provided in a participant&#146;s award agreement, in the event of a corporate transaction for
the portion of each award that is assumed or replaced, then such award will automatically become
fully vested and exercisable immediately upon termination of a participant&#146;s service if the
participant is terminated by the successor company or us without cause within twelve months after
the corporate transaction. For the portion of each award that is not assumed or replaced, such
portion of the award will automatically become fully vested and exercisable immediately prior to
the effective date of the corporate transaction so long as the participant&#146;s service has not been
terminated prior to such date.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In the event of a change in control, except as otherwise provided in a participant&#146;s award
agreement, following a change in control (other than a change in control that also is a corporate
transaction) and upon the termination of a participant&#146;s service without cause within twelve months
after a change in control, each award of such participant that is outstanding at such time will
automatically become fully vested and exercisable immediately upon the participant&#146;s termination.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under our 2006 Stock Incentive Plan, a corporate transaction is generally defined as:
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>a merger or consolidation in which we are not the surviving entity, except for the
principal purpose of changing our company&#146;s state of incorporation;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the sale, transfer or other disposition of all or substantially all of our assets;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the complete liquidation or dissolution of our Company;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>any reverse merger in which we are the surviving entity but our shares of common stock
outstanding immediately prior to such merger are converted or exchanged by virtue of the
merger into other property, whether in the form of securities, cash or otherwise, or in
which securities possessing more than forty percent (40%) of the total combined voting
power of our outstanding securities are transferred to a person or persons different from
those who held such securities immediately prior to such merger; or</TD>
</TR>




<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>
acquisition in a single or series of related transactions by any person or related group of persons
of beneficial ownership of securities possessing more than fifty percent (50%) of the total
combined voting power of our outstanding securities but excluding any such transaction or series of
related transactions that the plan administrator determines not to be a corporate transaction
(provided, however, that the administrator shall have no discretion in connection with a corporate
transaction for the purchase of all or substantially all of our shares unless the principal purpose
of such transaction is changing our Company&#146;s state of incorporation).
</TD></TR>

</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under our 2006 Stock Incentive Plan, a change of control is defined as:
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the direct or indirect acquisition by any person or related group of persons of
beneficial ownership of securities possessing more than fifty percent (50%) of the total
combined voting power of our outstanding securities pursuant to a tender or exchange offer
made</TD>
</TR>

</TABLE>
</DIV>
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</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR valign="top" style="font-size: 10pt; color: #textcolor#; background: #bgcolor#">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>directly to our stockholders and which a majority of the members of our board (who have
generally been on our board for at least 12&nbsp;months) who are not affiliates or associates of
the offeror do not recommend stockholders accept the offer, or</TD>
</TR>
<TR><TD>&nbsp;</TD></TR>

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>&#149;</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>a change in the composition of our board over a period of twelve months or less, such
that a majority of our board members ceases, by reason of one or more contested elections
for board membership, to be comprised of individuals who were previously directors of our
Company.</TD>
</TR>

</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Unless terminated sooner, the 2006 Stock Incentive Plan will automatically terminate in 2016.
Our Board of Directors has authority to amend, suspend or terminate our 2006 Stock Incentive Plan.
No amendment, suspension or termination of the 2006 Stock Incentive Plan shall adversely affect any
rights under awards already granted to a participant. To the extent necessary to comply with
applicable provisions of federal securities laws, state corporate and securities laws, the Internal
Revenue Code, the rules of any applicable stock exchange or national market system, and the rules
of any non-U.S. jurisdiction applicable to awards granted to residents therein (including the Tax
Ordinance), we shall obtain shareholder approval of any such amendment to the 2006 Stock Incentive
Plan in such a manner and to such a degree as required.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt">Impact of Israeli Tax Law
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The awards granted to employees pursuant to Section&nbsp;102 of the Tax Ordinance under the 2006
Stock Incentive Plan may be designated by us as approved options under the capital gains
alternative, or as approved options under the ordinary income tax alternative.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;To qualify for these benefits, certain requirements must be met, including registration of the
options in the name of a trustee. Each option, and any shares of common stock acquired upon the
exercise of the option, must be held by the trustee for a period commencing on the date of grant
and deposit into trust with the trustee and ending 24&nbsp;months thereafter.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under the terms of the capital gains alternative, we may not deduct expenses pertaining to the
options for tax purposes.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Under the 2006 Stock Incentive Plan, we may also grant to employees options pursuant to
Section 102(c) of the Tax Ordinance that are not required to be held in trust by a trustee. This
alternative, while facilitating immediate exercise of vested options and sale of the underlying
shares, will subject the optionee to the marginal income tax rate of up to 50% as well as payments
to the National Insurance Institute and health tax on the date of the sale of the shares or
options. Under the 2006 Stock Incentive Plan, we may also grant to non-employees options pursuant
to Section&nbsp;3(I) of the Tax Ordinance. Under that section, the income tax on the benefit arising to
the optionee upon the exercise of options and the issuance of common stock is generally due at the
time of exercise of the options.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Such options shall be further subject to the terms of the tax ruling that has been obtained by
Protalix Ltd. from the Israeli tax authorities in connection with the Merger. Under the tax
ruling, the options issued by us in connection with the assumption of 102 options previously issued
by Protalix Ltd. under the capital gains alternative shall be issued to a
</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->7<!-- /Folio -->
</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">



<DIV align="left" style="font-size: 10pt; margin-top: 6pt">trustee, shall be designated under the capital gains alternative and the issuance date of the
original options shall be deemed the issuance date for the assumed options for the calculation of
the respective holding period.
</DIV>
<!-- link1 "WHERE YOU CAN OBTAIN ADDITIONAL INFORMATION" -->
<DIV align="left"><A NAME="004"></A></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">WHERE YOU CAN OBTAIN ADDITIONAL INFORMATION
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;We are required to file annual, quarterly and special reports, proxy statements and other
information with the SEC. You may read and copy any document we file at the SEC&#146;s public reference
rooms at 100 F Street, N.E, Washington, D.C. 20549. You may also obtain copies of the documents at
prescribed rates by writing to the Public Reference Section of the SEC at 100 F Street, N.E., Room
1580, Washington, D.C. 20549. Please call the SEC at 1-800-SEC-0330 for more information on the
operation of the public reference rooms. Copies of our SEC filings are also available to the
public from the SEC&#146;s web site at www.sec.gov.
</DIV>


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</DIV>

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<DIV style="font-family: 'Times New Roman',Times,serif">




<DIV align="right" style="font-size: 10pt; margin-top: 12pt">EXHIBIT A
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">ARTICLES OF AMENDMENT
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">TO
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">ARTICLES OF INCORPORATION
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">OF
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">ORTHODONTIX, INC.
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">Document Number P95000091803
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1.&nbsp;The name of the corporation filing these Articles of Amendment is Orthodontix, Inc. (the
&#147;Corporation&#148;).
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2.&nbsp;Article&nbsp;I of the Articles of Incorporation of the Corporation is amended as follows to
change the Corporation&#146;s name:
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 12pt">Article&nbsp;I-Name
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The name of the corporation is Protalix BioTherapeutics, Inc. (the &#147;Corporation&#148;).
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3.&nbsp;The foregoing amendment was duly adopted by unanimous written consent of the directors and
a majority of the shareholders of the Corporation on December&nbsp;14, 2006.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;IN WITNESS WHEREOF, the undersigned President and Secretary of Orthodontix, Inc. have executed
these Articles of Amendment on behalf of the Corporation on this &#95;&#95;&#95;day of &#95;&#95;&#95;, 2007.
</DIV>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>
<TR>
    <TD valign="top" align="left">&nbsp;</TD>
    <TD colspan="3" align="left">ORTHODONTIX, INC.<BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/ David Aviezer, Ph.D.
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">David Aviezer, Ph.D.&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR>
    <TD colspan="5">&nbsp;</TD>
</TR>
</TABLE>


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