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<SEC-DOCUMENT>0000950136-07-006902.txt : 20071009
<SEC-HEADER>0000950136-07-006902.hdr.sgml : 20071008
<ACCEPTANCE-DATETIME>20071009063014
ACCESSION NUMBER:		0000950136-07-006902
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20071007
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20071009
DATE AS OF CHANGE:		20071009

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Protalix BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001006281
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				650643773
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33357
		FILM NUMBER:		071160799

	BUSINESS ADDRESS:	
		STREET 1:		2 SNUNIT ST
		STREET 2:		SCIENCE PARK, POB 455
		CITY:			CARMIEL
		STATE:			L3
		ZIP:			21000
		BUSINESS PHONE:		972-4-988-9488

	MAIL ADDRESS:	
		STREET 1:		2 SNUNIT ST
		STREET 2:		SCIENCE PARK, POB 455
		CITY:			CARMIEL
		STATE:			L3
		ZIP:			21000

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ORTHODONTIX INC
		DATE OF NAME CHANGE:	19980422

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
		DATE OF NAME CHANGE:	19960124
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>file1.htm
<DESCRIPTION>FORM 8-K
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<P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>UNITED STATES</B></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center><B>Washington, D.C. &nbsp;20549</B></P>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>______________</P>
<P style="margin:0px" align=center><BR></P>
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<P style="line-height:22px; margin:0px; padding-right:-9.6px; font-size:19.333px" align=center><B>FORM 8-K</B></P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:22px; margin:0px; padding-right:-9.6px; font-size:19.333px" align=center><B>CURRENT REPORT</B></P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center><B>Pursuant to Section 13 or 15(d)</B></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center><B>of the Securities Exchange Act of 1934</B></P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>______________</P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">Date of Report (Date of earliest event reported): &nbsp;October 7, 2007</P>
<P style="margin:0px"><BR></P>
<P style="line-height:22px; margin:0px; padding-right:-9.6px; font-size:19.333px" align="center"><B>Protalix BioTherapeutics, Inc.</B></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align="center">(Exact name of registrant as specified in its charter)</P>
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<TR><TD style="border-bottom:1px solid #000000" valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>Florida</P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-bottom:1px solid #000000" valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>000-27836</P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-bottom:1px solid #000000" valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>65-0643773</P>
</TD></TR>
<TR><TD valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>(State or other</P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>jurisdiction of</P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>incorporation)</P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>(Commission</P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>File Number)</P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>(IRS Employer</P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>Identification No.)</P>
</TD></TR>
<TR><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top colspan=3><P style="line-height:18.667px; margin:0px; padding-bottom:4px; font-size:16px;" align=center><B>2 Snunit Street</B></P>
<P style="line-height:18.667px; margin:0px; padding-bottom:4px; font-size:16px;" align=center><B>Science Park</B></P>
<P style="line-height:18.667px; margin:0px; padding-bottom:4px; font-size:16px;" align=center><B>POB 455</B></P>
<P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px; border-bottom:1px solid #000000" align=center><B>Carmiel, Israel 21000</B></P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top colspan=3><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px" align=center>(Address of principal executive offices) (Zip Code)</P>
</TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=20%><P style="font-size:2pt">&nbsp;</P></TD></TR>
</TABLE>
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<P style="margin:0px" align=center><BR></P>
<P style="margin:0px; font-size:16px" align=center>(Former Name or Former Address, if Changed Since Last Report)</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px">Registrant&#146;s telephone number, including area code: +972-4-988-9488</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px; "><img src="ebox.gif" width="10" height="10"><FONT FACE="Times New Roman"> &nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</FONT></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px; "><img src="ebox.gif" width="10" height="10"><FONT FACE="Times New Roman"> &nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</FONT></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px; "><img src="ebox.gif" width="10" height="10"><FONT FACE="Times New Roman"> &nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</FONT></P>
<P style="margin:0px; font-size:16px; padding-right:-9.6px; "><img src="ebox.gif" width="10" height="10"><FONT FACE="Times New Roman"> &nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) </FONT></P>
<P style="margin-top:5.533px; margin-bottom:13.333px"><BR>
<BR></P>
<P style="line-height:18.667px; margin:0px; font-size:16px" align=center><FONT FACE="Times New Roman">1</FONT></P>
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<P style="line-height:18.667px; margin-top:6.667px; margin-bottom:16px; font-size:16px"><B>Item 8.01. &nbsp;Other Events</B></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px">On October 7, 2007, Protalix BioTherapeutics, Inc. (the &#8220;Company&#8221;) issued a press release announcing that it had commenced a proposed underwritten public offering of its common stock pursuant to a preliminary prospectus supplement to its effective shelf registration statement. &nbsp;The press release is attached hereto as Exhibit 99.1.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px"><B>Item 9.01. &nbsp;Financial Statements and Exhibits</B></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; font-size:16px"><B>(d) </B></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; text-indent:48px; font-size:16px"><B>Exhibits </B></P>
<P style="line-height:18.667px; margin-top:6.667px; margin-bottom:-18.667px; font-size:16px">99.1</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:6.667px; text-indent:48px; font-size:16px">Press release dated October 7, 2007.</P>
<P style="margin-top:0px; margin-bottom:16px" align=center><BR>
<BR></P>
<P style="line-height:18.667px; margin:0px; font-size:16px" align="center">2</P>
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<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-family:Times New Roman Bold; font-size:16px" align=center><FONT FACE="Times New Roman Bold"><B>SIGNATURES</B></FONT></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:8px; font-size:16px"><FONT FACE="Times New Roman">Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</FONT></P>
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<TR><TD valign=top width=45%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top colspan=2><P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-family:Times New Roman Bold; font-size:16px"><FONT FACE="Times New Roman Bold"><B>PROTALIX BIOTHERAPEUTICS, INC.</B></FONT></P>
</TD></TR>
<TR><TD valign=top width=45%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=12%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=43%><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=45%><P style="line-height:18.667px; margin:0px; font-size:16px"><FONT FACE="Times New Roman">Date: October 8, 2007</FONT></P>
</TD><TD valign=top width=12%><P style="line-height:18.667px; margin:0px; font-size:16px">By:</P>
</TD><TD valign=top width=43%><P style="line-height:18.667px; margin:0px; font-size:16px"><U>/s/ David Aviezer&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></P>
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<TR><TD valign=top width=45%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=12%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">Name:</P>
</TD><TD valign=top width=43%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">David Aviezer, Ph.D.</P>
</TD></TR>
<TR><TD valign=top width=45%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=12%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">Title:</P>
</TD><TD valign=top width=43%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">President and</P>
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<TR><TD valign=top width=45%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=12%><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=43%><P style="line-height:18.667px; margin:0px; padding-right:-9.6px; font-size:16px">Chief Executive Officer</P>
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<DESCRIPTION>PRESS RELEASE DATED OCTOBER 7, 2007
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<P style="line-height:18.667px; margin:0px; font-size:16px" align=right>Exhibit 99.1</P>
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<P style="line-height:21.333px; margin-top:0px; margin-bottom:18.667px; font-size:18.667px" align=center><B>Protalix BioTherapeutics Announces Public Offering of Common Stock</B></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px"><B>CARMIEL, Israel &#150; October 7, 2007 &#150; </B>Protalix BioTherapeutics, Inc. (Amex: PLX), today announced that it has commenced a proposed underwritten public offering of its common stock pursuant to a preliminary prospectus supplement to its effective shelf registration statement. &nbsp;The company is proposing to sell 3,726,708 shares of its common stock and certain selling securityholders are proposing to sell an aggregate of 1,242,236 shares of common stock. &nbsp;The selling securityholders have also granted a 30-day over-allotment option to the underwriters to purchase a number of shares equal to 15% of the aggregate number of shares sold in the initial offering. &nbsp;As the company is endeavoring to raise gross proceeds of approximately $130 million, it may be required to increase the number of its shares to be sold in the proposed offering if the offering price, as determined through negotiation between the co
mpany and its underwriters, is lower than the current trading range of the company&#146;s common stock on the American Stock Exchange. &nbsp;Protalix BioTherapeutics will not receive any proceeds from the sale of shares of common stock by the selling securityholders.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px">UBS Securities LLC is acting as sole book-running manager for this offering. &nbsp;CIBC World Markets Corp. is acting as a co-manager for this offering. </P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px">This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such jurisdiction. </P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px">Copies of the preliminary prospectus supplement and accompanying prospectus may be obtained from UBS Investment Bank, Attn: Prospectus Department, 299 Park Avenue, New York, NY 10171, Toll Free: (888) 827-7275.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px"><B>About Protalix BioTherapeutics, Inc.</B></P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px">Protalix is a biopharmaceutical company. &nbsp;Its goal is to become a fully integrated biopharmaceutical company focused on the development and commercialization of proprietary recombinant therapeutic proteins to be expressed through its proprietary plant cell based protein expression system, ProCellEx<SUP>TM</SUP>. &nbsp;ProCellEx presents a proprietary method for the expression of recombinant proteins that Protalix believes is safe and scalable and will allow for the cost-effective, industrial-scale production of recombinant therapeutic proteins. &nbsp;Protalix has initiated enrollment and treatment of patients in its pivotal phase III clinical trial of its lead product candidate, prGCD, for enzyme replacement therapy of Gaucher disease, a lysosomal storage disorder in humans. &nbsp;The final design of the pivotal phase III clinical trial is based on an agreement reached by Protalix with the United States Food and 
Drug Administration, through its Special Protocol Assessment (SPA). &nbsp;Protalix is also advancing additional recombinant biopharmaceutical drug development programs.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:16px; font-size:16px"><B>Safe Harbor Statement:</B></P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px">To the extent that statements in this press release are not strictly historical, all such statements are forward-looking, and are made pursuant to the safe-harbor provisions of the Private Securities Litigation Reform Act of 1995. &nbsp;These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. &nbsp;These statements are based on our current beliefs and expectations as to such future outcomes. &nbsp;</P>
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<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px">Drug discovery and development involve a high degree of risk. &nbsp;Factors that might cause such a material difference include, among others, uncertainties related to the ability to attract and retain partners for our technologies and products under development, the identification of lead compounds, the successful preclinical development of our products, the completion of clinical trials, the review process of the FDA, foreign regulatory bodies and other governmental regulation, and other factors described in our filings with the Securities and Exchange Commission. &nbsp;The statements are valid only as of the date hereof and we disclaim any obligation to update this information.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px"><B>For additional information, contact Protalix BioTherapeutics at:<BR>
</B> <FONT COLOR=#0000FF><U>investors@protalix.com</U></FONT> &nbsp;</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px"><B>AMEX IR Alliance for Protalix BioTherapeutics<BR>
</B>Lee Roth / David Burke<BR>
212-896-1209 / 1258<BR>
<FONT COLOR=#0000FF><U>lroth@kcsa.com</U></FONT> / <FONT COLOR=#0000FF><U>dburke@kcsa.com</U></FONT> <B>&nbsp;</B></P>
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