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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001144204-09-042135.txt : 20090811
<SEC-HEADER>0001144204-09-042135.hdr.sgml : 20090811
<ACCEPTANCE-DATETIME>20090811185512
ACCESSION NUMBER:		0001144204-09-042135
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20090807
FILED AS OF DATE:		20090811
DATE AS OF CHANGE:		20090811

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			FROST PHILLIP MD ET AL
		CENTRAL INDEX KEY:			0000898860

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33357
		FILM NUMBER:		091004973

	MAIL ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137-3227

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Protalix BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001006281
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				650643773
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2 SNUNIT ST
		STREET 2:		SCIENCE PARK, POB 455
		CITY:			CARMIEL
		STATE:			L3
		ZIP:			20100
		BUSINESS PHONE:		972-4-988-9488

	MAIL ADDRESS:	
		STREET 1:		2 SNUNIT ST
		STREET 2:		SCIENCE PARK, POB 455
		CITY:			CARMIEL
		STATE:			L3
		ZIP:			20100

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ORTHODONTIX INC
		DATE OF NAME CHANGE:	19980422

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
		DATE OF NAME CHANGE:	19960124

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Frost Gamma Investments Trust
		CENTRAL INDEX KEY:			0001380896

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33357
		FILM NUMBER:		091004972

	BUSINESS ADDRESS:	
		STREET 1:		4400 BISCAYNE BOULEVARD, 15TH FLOOR
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137
		BUSINESS PHONE:		305-575-6000

	MAIL ADDRESS:	
		STREET 1:		4400 BISCAYNE BOULEVARD, 15TH FLOOR
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137

	FORMER NAME:	
		FORMER CONFORMED NAME:	Frost Gamma Investment Trust
		DATE OF NAME CHANGE:	20061113
</SEC-HEADER>
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    <footnotes>
        <footnote id="F1">These securities are held by Frost Gamma Investments Trust, of which the Reporting Person is the trustee.  Frost Gamma
 Limited Partnership is the sole and exclusive beneficiary of Frost Gamma Investments Trust.  The Reporting Person is one of
 two limited partners of Frost Gamma Limited Partnership.  The general partner of Frost Gamma Limited Partnership is Frost
 Gamma, Inc., and the sole shareholder of Frost Gamma, Inc. is Frost-Nevada Corporation, of which  the Reporting Person is
 the sole shareholder.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Phillip Frost, M.D.</signatureName>
        <signatureDate>2009-08-11</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Phillip Frost, M.D., as Trustee</signatureName>
        <signatureDate>2009-08-11</signatureDate>
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</ownershipDocument>
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<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>v157346_ex99.htm
<TEXT>
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  <head>
    <title>Unassociated Document</title>
    <!--Licensed to: Vintage Filings-->
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99</font></div>
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Joint Filer Information</font></div>
      <div>
        <div align="left">
          <div align="left">
            <table cellpadding="0" cellspacing="0" width="100%">
                <tr>
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                <tr>
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                <tr>
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                <tr>
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                  <td align="left" valign="top" width="78%">
                    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">Phillip
      Frost, M.D.</font></div>
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                <tr>
                  <td valign="top" width="22%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">&#160;
      </font></td>
                  <td valign="top" width="78%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">&#160;
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                    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">Issuer
      &amp; Ticker Symbol:</font></div>
                  </td>
                  <td valign="top" width="78%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">      </font>
                    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">Protalix
      BioTherapeutics, Inc. (&#8220;PLX&#8221;)</font></div>
                  </td>
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                <tr>
                  <td valign="top" width="22%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">&#160;
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                  </td>
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      of Event Requiring <font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">Statement:</font></font></div>
                  </td>
                  <td valign="top" width="78%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">      </font>
                    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">August
      7, 2009</font></div>
                  </td>
                </tr>
                <tr>
                  <td valign="top" width="22%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">&#160;
      </font></td>
                  <td valign="top" width="78%"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: times new roman">&#160;
      </font></td>
                </tr>
            </table>
          </div>
        </div>
      </div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Signature:
<font style="DISPLAY: inline; TEXT-DECORATION: underline">/s/ Phillip Frost,
M.D., Trustee</font></font></div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 9pt; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Phillip
Frost, M.D., Trustee</font></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
      <div style="DISPLAY: block; TEXT-INDENT: 0pt"><br></div>
    </div>
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