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Significant Accounting Policies - Additional Information (Detail) (USD $)
In Millions, except Share data, unless otherwise specified
6 Months Ended 31 Months Ended 3 Months Ended 6 Months Ended
Jun. 30, 2012
Entity
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Protalix Bio Therapeutics Incorporation
Jun. 30, 2012
Pfizer Incorporation
Jun. 30, 2012
Stock Options
Jun. 30, 2011
Stock Options
Jun. 30, 2012
Stock Options
Jun. 30, 2011
Stock Options
Jun. 30, 2012
Upon Filing of Pediatric Investigation Plan to EMA
Jun. 30, 2012
Upon each FDA and European Medicine Agency approval
Significant Accounting Policies [Line Items]                      
Number of Subsidiaries 2                    
Pfizer Agreement, upfront payment received   $ 60.0               $ 5.0  
Milestone payment triggered                     $ 25.0
Pfizer Agreement, future revenues and expense sharing percentage       40.00% 60.00%            
Common stock, par value per share $ 0.001 $ 0.001 $ 0.001                
Options to purchase common stock not included in diluted LPS because the effect would be anti-dilutive           1,785,542 7,435,271 1,785,542 7,537,094