    <SEC-DOCUMENT>0001144204-18-052765-index.html : 20181005
    <SEC-HEADER>0001144204-18-052765.hdr.sgml : 20181005
    <ACCEPTANCE-DATETIME>20181005171057
    ACCESSION NUMBER:		0001144204-18-052765
    CONFORMED SUBMISSION TYPE:	PRE 14A
    PUBLIC DOCUMENT COUNT:		5
    CONFORMED PERIOD OF REPORT:	20181213
    FILED AS OF DATE:		20181005
    DATE AS OF CHANGE:		20181005

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Protalix BioTherapeutics, Inc.
    		CENTRAL INDEX KEY:			0001006281
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				650643773
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		PRE 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33357
    		FILM NUMBER:		181111281

    	BUSINESS ADDRESS:
    		STREET 1:		2 SNUNIT ST
    		STREET 2:		SCIENCE PARK, POB 455
    		CITY:			CARMIEL
    		STATE:			L3
    		ZIP:			20100
    		BUSINESS PHONE:		972-4-988-9488

    	MAIL ADDRESS:
    		STREET 1:		2 SNUNIT ST
    		STREET 2:		SCIENCE PARK, POB 455
    		CITY:			CARMIEL
    		STATE:			L3
    		ZIP:			20100

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ORTHODONTIX INC
    		DATE OF NAME CHANGE:	19980422

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
    		DATE OF NAME CHANGE:	19960124
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>PRE 14A
    <SEQUENCE>1
    <FILENAME>tv504256-pre14a.htm
    <DESCRIPTION>PRELIMINARY PROXY STATEMENT
    <TEXT>
    Document 1 - file: tv504256-pre14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_protalix.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_protalix.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>sig_yossi-maimon.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: sig_yossi-maimon.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tv504256_pc1.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tv504256_pc1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>tv504256_pc2.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: tv504256_pc2.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>