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SIGNIFICANT ACCOUNTING POLICIES (Additional Information) (Details) $ / shares in Units, $ in Thousands |  |  |  |  | 1 Months Ended | 3 Months Ended
--- | --- | --- | --- | --- | --- | ---
Jul. 02, 2021 USD ($) $ / shares shares | May 13, 2021 USD ($) | Jul. 23, 2018 USD ($) | Oct. 19, 2017 USD ($) | Oct. 31, 2015 | Mar. 31, 2022 USD ($) agreement $ / shares shares | Mar. 31, 2021 USD ($) $ / shares shares
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares |  |  |  |  |  | $ 0.001 | $ 0.001
Gross proceeds |  |  |  |  |  |  | $ 8,575
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | shares |  |  |  |  |  | 33,004,217 | 26,769,693
2021 Notes |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Interest rate (as a percent) |  |  |  |  |  |  | 7.50%
2024 Notes |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Interest rate (as a percent) |  |  |  |  |  | 7.50% |
Maintain of Minimum Cash Balance |  |  |  |  |  | $ 7,500 |
Amended Pfizer Agreement | Protalix Bio Therapeutics Incorporation [Member] | Brazil [Member] |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Collaborative Arrangement Revenues Expenses Sharing Percentage |  |  |  |  | 100.00% |  |
Chiesi US Agreement and Chiesi Ex US Agreement [Member] |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Non-refundable Payment Receivable |  |  | $ 25,000 | $ 25,000 |  |  |
Chiesi Agreements |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Performance obligation number | agreement |  |  |  |  |  | 2 |
Chiesi US Agreement [Member] |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Additional Amounts Payable To Cover Development Costs |  |  | 20,000 |  |  |  |
Maximum entitlement of development costs to cover per year |  |  | 7,500 |  |  |  |
Additional amount payable for achievement of regulatory and commercial milestones |  |  | $ 760,000 |  |  |  |
Chiesi US Agreement [Member] | Minimum |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Payment On Net Sales Percentage |  |  | 15.00% |  |  |  |
Chiesi US Agreement [Member] | Maximum |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Payment On Net Sales Percentage |  |  | 40.00% |  |  |  |
Chiesi Ex US Agreement [Member] |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Additional Amounts Payable To Cover Development Costs |  |  |  | 25,000 |  |  |
Maximum entitlement of development costs to cover per year |  |  |  | 10,000 |  |  |
Additional amount payable for achievement of regulatory and commercial milestones |  |  |  | $ 320,000 |  |  |
Change in amount receivable for achievement of regulatory and commercial milestones |  | $ 25,000 |  |  |  |  |
Agreement Amendment Payment Receivable |  | $ 10,000 |  |  |  |  |
Chiesi Ex US Agreement [Member] | Minimum |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Payment On Net Sales Percentage |  |  |  | 15.00% |  |  |
Chiesi Ex US Agreement [Member] | Maximum |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Payment On Net Sales Percentage |  |  |  | 35.00% |  |  |
ATM Shares |  |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares | $ 0.001 |  |  |  |  |  |
Sale of stock, maximum offering price | $ 20,000 |  |  |  |  |  |
Number of shares issued (in shares) | shares | 3,296,123 |  |  |  |  |  |
Gross proceeds | $ 13,800 |  |  |  |  |  |

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