<SEC-DOCUMENT>0001104659-23-062301-index.html : 20230518
<SEC-HEADER>0001104659-23-062301.hdr.sgml : 20230518
<ACCEPTANCE-DATETIME>20230518170017
ACCESSION NUMBER:		0001104659-23-062301
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		5
CONFORMED PERIOD OF REPORT:	20230628
FILED AS OF DATE:		20230518
DATE AS OF CHANGE:		20230518

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Protalix BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001006281
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				650643773
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33357
		FILM NUMBER:		23936914

	BUSINESS ADDRESS:	
		STREET 1:		2 UNIVERSITY PLAZA
		STREET 2:		SUITE 100
		CITY:			HACKENSACK
		STATE:			NJ
		ZIP:			07601
		BUSINESS PHONE:		201-696-9345

	MAIL ADDRESS:	
		STREET 1:		2 UNIVERSITY PLAZA
		STREET 2:		SUITE 100
		CITY:			HACKENSACK
		STATE:			NJ
		ZIP:			07601

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ORTHODONTIX INC
		DATE OF NAME CHANGE:	19980422

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
		DATE OF NAME CHANGE:	19960124
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>tm232158-3_def14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: tm232158-3_def14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>lg_protalix-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_protalix-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>sg_eyalrubin-bw.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: sg_eyalrubin-bw.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>px_protalixproxy1pg01-bwlr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: px_protalixproxy1pg01-bwlr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>px_protalixproxy1pg02-bwlr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: px_protalixproxy1pg02-bwlr.jpg

</DOCUMENT>
</SEC-DOCUMENT>