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COMMERCIALIZATION AGREEMENTS (Details) - USD ($) $ in Thousands		1 Months Ended		12 Months Ended
	Mar. 29, 2021	Jul. 23, 2018	Oct. 19, 2017	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	May 13, 2021	Oct. 31, 2015
Payment for promissory note				$ 0	$ 0	$ 4,086
Pfizer
Promissory note								$ 4,300
Payment for promissory note	$ 4,000
Chiesi Agreements
Non-refundable payment receivable		$ 25,000	$ 25,000	50,000
Payments in consideration for development services performed				45,000
Payments in connection with performance of additional studies				51,300
Agreement amendment payment receivable				30,000
Chiesi US Agreement
Additional amounts payable to cover development costs		20,000
Maximum entitlement of development costs to cover per year		7,500
Additional amount payable for achievement of regulatory and commercial milestones		$ 760,000		$ 735,000
Chiesi US Agreement | Maximum
Payment on net sales percentage		40.00%		40.00%
Chiesi US Agreement | Minimum
Payment on net sales percentage		15.00%		15.00%
Chiesi Ex-US Agreement
Additional amounts payable to cover development costs			25,000
Maximum entitlement of development costs to cover per year			10,000
Additional amount payable for achievement of regulatory and commercial milestones			$ 320,000
Agreement amendment payment receivable							$ 10,000
Chiesi Ex-US Agreement | Maximum
Payment on net sales percentage			35.00%	35.00%
Chiesi Ex-US Agreement | Minimum
Payment on net sales percentage			15.00%	15.00%

X

- Definition

The total amount payable to entity for the achievement of regulatory and commercial milestones.

+ References

No definition available.

+ Details

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- Definition

The maximum amount payable to the entity to cover development costs under agreement.

+ References

No definition available.

+ Details

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- Definition

Agreement Amendment Payment Receivable

+ References

No definition available.

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- Definition

The maximum amount payable to entity to cover development costs in any year under agreement.

+ References

No definition available.

+ Details

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- Definition

The cash inflow from consideration received for development services performed.

+ References

No definition available.

+ Details

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- Definition

Represents the payment as a percentage of future net sales.

+ References

No definition available.

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- Definition

The cash inflow in connection with performance of additional studies.

+ References

No definition available.

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- Definition

The amount of upfront, non refundable and non creditable payment receivable under the agreement for licensing rights.

+ References

No definition available.

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- Definition

Sum of the carrying values as of the balance sheet date of the portions of long-term notes payable due within one year or the operating cycle if longer.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.19,20)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1

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- Definition

The cash outflow for a borrowing supported by a written promise to pay an obligation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482740/230-10-45-15

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