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COMMERCIALIZATION AGREEMENTS (Details) - USD ($) $ in Millions | Jul. 23, 2018 | Oct. 19, 2017 | Dec. 31, 2024
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Chiesi US Agreement |  |  |
Non-refundable payment receivable | $ 25.0 |  |
Additional amounts payable to cover development costs | 20.0 |  |
Maximum entitlement of development costs to cover per year | 7.5 |  |
Additional amount payable for achievement of regulatory and commercial milestones | $ 760.0 |  | $ 735.0
Chiesi US Agreement | Maximum |  |  |
Payment on net sales percentage | 40.00% |  |
Chiesi US Agreement | Minimum |  |  |
Payment on net sales percentage | 15.00% |  |
Chiesi Ex-US Agreement |  |  |
Non-refundable payment receivable |  | $ 25.0 |
Additional amounts payable to cover development costs |  | 25.0 |
Maximum entitlement of development costs to cover per year |  | 10.0 |
Additional amount payable for achievement of regulatory and commercial milestones |  | $ 320.0 |
Chiesi Ex-US Agreement | Maximum |  |  |
Payment on net sales percentage |  | 35.00% |
Chiesi Ex-US Agreement | Minimum |  |  |
Payment on net sales percentage |  | 15.00% |

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- Definition The total amount payable to entity for the achievement of regulatory and commercial milestones. + References No definition available. + Details
Name: | plx_AdditionalAmountPayableForAchievementOfRegulatoryAndCommercialMilestones
Namespace Prefix: | plx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition The maximum amount payable to the entity to cover development costs under agreement. + References No definition available. + Details
Name: | plx_AdditionalAmountsPayableToCoverDevelopmentCosts
Namespace Prefix: | plx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition The maximum amount payable to entity to cover development costs in any year under agreement. + References No definition available. + Details
Name: | plx_MaximumEntitlementOfDevelopmentCostsToCoverPerYear
Namespace Prefix: | plx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Represents the payment as a percentage of future net sales. + References No definition available. + Details
Name: | plx_PaymentOnNetSalesPercentage
Namespace Prefix: | plx_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | duration

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- Definition The amount of upfront, non refundable and non creditable payment receivable under the agreement for licensing rights. + References No definition available. + Details
Name: | plx_UpfrontNonrefundableNoncreditablePaymentReceivable
Namespace Prefix: | plx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Details
Name: | us-gaap_TypeOfArrangementAxis=plx_ChiesiUSAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_RangeAxis=srt_MaximumMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_RangeAxis=srt_MinimumMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_TypeOfArrangementAxis=plx_ChiesiExUSAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |