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<SEC-DOCUMENT>0001299933-10-003140.txt : 20100819
<SEC-HEADER>0001299933-10-003140.hdr.sgml : 20100819
<ACCEPTANCE-DATETIME>20100819165920
ACCESSION NUMBER:		0001299933-10-003140
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20100819
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20100819
DATE AS OF CHANGE:		20100819

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			STEMCELLS INC
		CENTRAL INDEX KEY:			0000883975
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				943078125
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19871
		FILM NUMBER:		101028327

	BUSINESS ADDRESS:	
		STREET 1:		3155 PORTER DRIVE
		STREET 2:		.
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		6504753100

	MAIL ADDRESS:	
		STREET 1:		3155 PORTER DRIVE
		STREET 2:		.
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTOTHERAPEUTICS INC/DE
		DATE OF NAME CHANGE:	19930328
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>htm_38788.htm
<DESCRIPTION>LIVE FILING
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<TITLE> StemCells, Inc. (Form: 8-K) </TITLE>
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		UNITED STATES<BR>
	SECURITIES AND EXCHANGE COMMISSION
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<BR>
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	WASHINGTON, D.C. 20549
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<P ALIGN="CENTER">
<FONT SIZE="5">
	FORM 8-K
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<FONT SIZE="3">
	CURRENT REPORT
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	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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	Date of Report (Date of Earliest Event Reported):
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	&nbsp;
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	August 19, 2010
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	StemCells, Inc.
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<BR>__________________________________________<BR>
	(Exact name of registrant as specified in its charter)
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	Delaware
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	000-19871
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	94-3078125
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_____________________<BR>
	(State or other jurisdiction
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	(Commission
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	(I.R.S. Employer
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	of incorporation)
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	File Number)
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	Identification No.)
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	3155 Porter Drive, Palo Alto, California
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	&nbsp;
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	94304
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_________________________________<BR>
	(Address of principal executive offices)
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	&nbsp;
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___________<BR>
	(Zip Code)
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	Registrant&#146;s telephone number, including area code:
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	650.475.3100
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<P ALIGN="CENTER">
<FONT SIZE="2">
	Not Applicable
<BR>______________________________________________<BR>
	Former name or former address, if changed since last report
</FONT>
<P ALIGN="CENTER">
<FONT SIZE="2">
	&nbsp;
</FONT>
<!-- CoverPageRegistrant END --><P><FONT SIZE="2">
Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:</FONT>
</P>
<P><FONT SIZE="2">
[&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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<FONT SIZE="2">Top of the Form</FONT>
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<B>
	Item 8.01 Other Events.
</B>
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<FONT SIZE="2">
On August 19, 2010, StemCells, Inc. (the "Company") announced the publication of new preclinical data demonstrating that the Company&#x2019;s proprietary human neural stem cells can restore lost motor function in mice with chronic spinal cord injury.  The full text of this press release is attached hereto as Exhibit 99.1.
</FONT>
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	Item 9.01 Financial Statements and Exhibits.
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<FONT SIZE="2">
(d) Exhibits<br><br>Exhibit 99.1 Press Release of StemCells, Inc. dated August 19, 2010
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<B>
	SIGNATURES
</B>
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	Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
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	StemCells, Inc.
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	&nbsp;&nbsp;
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<I>
	August 19, 2010
</I>
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</TD>
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<FONT SIZE="2">
	&nbsp;
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<I>
	By:
</I>
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	&nbsp;
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<I>
	/s/ Kenneth Stratton
</I>
<BR>
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	&nbsp;
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<I>
	Name: Kenneth Stratton
</I>
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<I>
	Title: General Counsel
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	Exhibit&nbsp;Index
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	Exhibit No.
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	Description
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	99.1
</DIV>
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	&nbsp;
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Press Release of StemCells, Inc. dated August 19, 2010
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<TYPE>EX-99.1
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<BODY style="font-family: 'Times New Roman',Times,serif">


<P align="right" style="font-size: 10pt"><FONT style="font-size: 20pt">NEWS RELEASE</FONT>



<P align="left" style="font-size: 20pt"><FONT style="font-size: 12pt"><B><I>FOR IMMEDIATE RELEASE</I></B>
</FONT>
<DIV align="center">
<TABLE style="font-size: 12pt" cellspacing="0" border="0" cellpadding="0" width="95%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="16%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="41%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="38%">&nbsp;</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom" style="font-size: 12pt">
    <TD align="left" valign="top"><FONT style="font-size: 10pt"><B>CONTACT:</B></FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><FONT style="font-size: 10pt">Investor Inquiries</FONT>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><FONT style="font-size: 10pt">Media</FONT></TD>
</TR>
<TR style="font-size: 1px">
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top" style="border-top: 1px solid #000000"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom" style="font-size: 10pt">
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><FONT style="font-size: 10pt">Megan Meloni<BR>
StemCells, Inc.<BR>
(650)&nbsp;475-3100, ext. 105</FONT>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><FONT style="font-size: 10pt">Tim Brons<BR>
Vida Communication, Inc.<BR>
(415)&nbsp;675-7402</FONT></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="center" style="font-size: 10pt"><FONT style="font-size: 10.5pt"><B>STEMCELLS, INC REPORTS BREAKTHROUGH USING HUMAN NEURAL STEM CELLS TO RESTORE MOTOR FUNCTION<BR>
IN CHRONIC SPINAL CORD INJURY</B></FONT>



<P align="center" style="font-size: 10.5pt"><FONT style="font-size: 10pt"><B><I>Newly Published Study Shows Long-Term Reversal of Hind Limb Paralysis in<BR>
Spinal Cord Injured Mice</I></B></FONT>



<P align="left" style="font-size: 10pt; text-indent: 4%"><B>PALO ALTO, Calif., August&nbsp;19, 2010 </B>&#150; StemCells, Inc. (NASDAQ: STEM), announced today the
publication of new preclinical data demonstrating that the Company&#146;s proprietary human neural stem
cells restore lost motor function in mice with chronic spinal cord injury. This is the first
published study to show that human neural stem cells can restore mobility even when administered at
time points beyond the acute phase of trauma, suggesting the prospect of treating a much broader
population of injured patients than previously demonstrated. This groundbreaking study, entitled
&#147;Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal
Cord Injury NOD-<I>scid </I>Mouse Model,&#148; was led by Dr.&nbsp;Aileen Anderson of the Sue and Bill Gross Stem
Cell Research Center at the University of California, Irvine (UCI). The paper was published
yesterday in the international peer-reviewed journal <I>PLoS ONE</I>, and is available online at
<U>http://dx.plos.org/10.1371/journal.pone.0012272</U>.


<P align="left" style="font-size: 10pt; text-indent: 4%">In this latest study, StemCells&#146; human neural stem cells were transplanted into mice 30&nbsp;days
after a spinal cord injury that results in hind limb paralysis. The transplanted mice demonstrated
a significant and persistent recovery of walking ability in two separate tests of motor function
when compared to control groups. These results are particularly significant because it is the first
time that human neural stem cells have been shown to promote functional recovery in a chronic
spinal cord injury setting, which is characterized as a point in time after injury in which
inflammation has stabilized and behavioral recovery has reached a plateau. In humans, the chronic
phase typically does not set in until several weeks or months following the injury.


<P align="left" style="font-size: 10pt; text-indent: 4%">&#147;These exciting results demonstrate an expanded window of opportunity for human neural stem
cell intervention in spinal cord injury,&#148; stated Stephen Huhn, MD, FACS, FAAP, Vice President and
Head of the CNS Program at StemCells, Inc. &#147;1.3&nbsp;million individuals in the U.S. are living with
chronic spinal cord injury, and this latest study provides additional evidence that the use of our
human neural stem cells may be a viable treatment approach for them. The strong preclinical data
we have accumulated to date will enable our transition to a clinical trial, which we plan to
initiate in 2011.&#148;


<P align="left" style="font-size: 10pt; text-indent: 4%">Aileen Anderson, Ph.D., Associate Professor in the Departments of Physical Medicine and
Rehabilitation, and Anatomy and Neurobiology at UCI, added, &#147;Human neural stem cells are a novel
therapeutic approach that holds much promise for spinal cord injury. However, published research to
date has generally focused on the acute and sub-acute phases. As part of our long-standing
collaboration with StemCells, we have pursued a thoughtful and deliberate research strategy to
establish the groundwork necessary to advance this cell-based approach into the clinic. This
latest study builds on the extensive work we had previously published in the sub-acute phase of
injury, and offers additional hope to those who are paralyzed or have impaired motor function.&#148;


<P align="left" style="font-size: 10pt"><B>About the Sue and Bill Gross Stem Cell Research Center</B>


<P align="left" style="font-size: 10pt; text-indent: 4%">The Sue and Bill Gross Stem Cell Research Center promotes basic and clinical research and
training in the field of stem cell biology at the University of California, Irvine. The Center is a
leading international institution in stem cell research and clinical applications, consolidating
existing research strengths and clinical initiatives at UCI and serving as a nucleus for growth via
collaboration and new recruits. The Center provides an organizational structure for all areas of
stem cell research, contributes to premier graduate training, maintains a core stem cell facility
and equipment resources, hosts guest researchers and annual meetings, and contributes to the
research and dialogue on the policy and ethical issues related to stem cells. For more information,
see <U>http://stemcell.uci.edu/index.cfm</U>.


<P align="left" style="font-size: 10pt"><B>About StemCells, Inc.</B>


<P align="left" style="font-size: 10pt; text-indent: 4%">StemCells, Inc. is engaged in the research, development, and commercialization of stem cell
therapeutics and tools for use in stem cell-based research and drug discovery. In its therapeutic
product development programs, StemCells is targeting diseases of the central nervous system and
liver. StemCells&#146; lead product candidate, HuCNS-SC<sup>&#174;</sup> cells (purified human neural stem
cells), is in clinical development for the treatment of two fatal neurodegenerative disorders that
primarily affect young children. StemCells also markets specialty cell culture products under the
SC Proven<sup>&#174; </sup>brand, and is developing stem cell-based assay platforms for use in
pharmaceutical research, drug discovery and drug development. The Company has exclusive rights to
approximately 55 issued or allowed U.S. patents and over 200 granted or allowed non-U.S. patents.
Further information about StemCells is available at <U>www.stemcellsinc.com</U>.


<P align="left" style="font-size: 10pt; text-indent: 4%"><I>Apart from statements of historical fact, the text of this press release constitutes
forward-looking statements within the meaning of the U.S. securities laws, and is subject to the
safe harbors created therein. These statements include, but are not limited to, the potential of
the Company&#146;s human neural stem cells to one day treat a broad population of spinal cord injured
patients; the prospect and timing associated with initiating a clinical trial in spinal cord
injury; and statements regarding the future business operations of StemCells, Inc. (the &#147;Company&#148;).
These forward-looking statements speak only as of the date of this news release. The Company does
not undertake to update any of these forward-looking statements to reflect events or circumstances
that occur after the date hereof. Such statements reflect management&#146;s current views and are based
on certain assumptions that may or may not ultimately prove valid. The Company&#146;s actual results may
vary materially from those contemplated in such forward-looking statements due to risks and
uncertainties to which the Company is subject, including uncertainties with respect to the fact
that additional trials will be required to confirm the safety and demonstrate the efficacy of the
Company&#146;s HuCNS-SC cells for the treatment of central nervous system disorders, including spinal
cord injury; risks whether the FDA or other applicable regulatory agencies will permit the Company
to continue clinical testing in NCL, PMD or in future clinical trials of proposed therapies for
spinal cord injury or other diseases or conditions; uncertainties about the design of future
clinical trials and whether the Company will receive the necessary support of a clinical trial site
and its institutional review board to pursue future clinical trials; uncertainties regarding the
Company&#146;s ability to obtain the increased capital resources needed to continue its current and
planned research and development operations, including such operations of the Company for
non-therapeutic applications, and to conduct the research, preclinical development and clinical
trials necessary for regulatory approvals; uncertainty as to whether HuCNS-SC cells and any
products that may be generated in the future in the Company&#146;s cell-based programs will prove safe
and clinically effective and not cause tumors or other adverse side effects; uncertainties
regarding whether results in preclinical research in animals will be indicative of future clinical
results in humans; uncertainties regarding the Company&#146;s manufacturing capabilities given its
increasing preclinical and clinical commitments; uncertainties regarding the validity and
enforceability of the Company&#146;s patents; uncertainties as to whether the Company will become
profitable; and other factors that are described under the heading &#147;Risk Factors&#148; disclosed in Part
I, Item&nbsp;1A in the Company&#146;s Annual Report on </I><I>Form 10-K</I><I> for the year ended December&nbsp;31, 2009.</I>


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