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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Cash flows from operating activities:    
Net loss $ (10,229,439) $ (5,747,235)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 271,397 305,041
Stock-based compensation 736,545 934,464
Gain on disposal of fixed assets 0 (31)
Change in fair value of warrant liability 4,941,177 (1,782,955)
Changes in operating assets and liabilities:    
Other receivables 20,921 (71,021)
Trade receivables (44,791) 41,473
Prepaid and other current assets 134,673 (5,766)
Other assets, non-current 8,081 3,012
Accounts payable and accrued expenses (1,163,949) (1,183,647)
Accrued wind-down expenses (315,466) (293,044)
Deferred revenue (8,859) (15,921)
Deferred rent 19,031 397,300
Net cash used in operating activities (5,630,679) (7,418,330)
Cash flows from investing activities:    
Purchase of marketable securities (2,076,356) (8,382,861)
Proceeds from the sale and maturity of marketable securities 3,212,000 0
Purchases of property, plant and equipment (4,300) (16,637)
Proceeds from sale of property, plant and equipment 0 35,427
Net cash provided by (used in) investing activities 1,131,344 (8,364,071)
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs 0 9,399,003
Proceeds from the exercise of stock options 0 880
Proceeds from the exercise of warrants, net of issuance costs 728,623 0
Payments related to net share issuance of stock based awards (13,536) (197,757)
Repayment of capital lease obligations (17,979) (16,333)
Repayment of bonds payable (46,250) (42,500)
Net cash provided by financing activities 650,858 9,143,293
Decrease in cash and cash equivalents (3,848,477) (6,639,108)
Effects of foreign exchange rate changes on cash (8,031) (2,528)
Cash and cash equivalents, beginning of period 13,311,261 19,707,821
Cash and cash equivalents, end of period 9,454,753 13,066,185
Supplemental disclosure of cash flow information:    
Interest paid $ 14,447 $ 20,207