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Stock-Based Compensation (Tables) | 6 Months Ended
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Jun. 30, 2012
Stock-Based Compensation [Abstract] |
Stock-based compensation expense |
|  | Three months ended June 30, |  |  | Six months ended June 30, |
|  | 2012 |  |  | 2011 |  |  | 2012 |  |  | 2011 |
Research and development expense |  | $ | 320,303 |  |  | $ | 522,958 |  |  | $ | 652,177 |  |  | $ | 961,001 |
Selling, general and administrative expense |  |  | 403,142 |  |  |  | 491,305 |  |  |  | 807,813 |  |  |  | 987,726 |
Total employee stock-based compensation |  | $ | 723,445 |  |  | $ | 1,014,263 |  |  | $ | 1,459,990 |  |  | $ | 1,948,727 |
Effect on basic and diluted net income (loss) per share |  | $ | (0.03 | ) |  | $ | (0.07 | ) |  | $ | (0.06 | ) |  | $ | (0.14 | )
Stock option activity |
|  | Number of options |  |  | Weighted-average exercise price ($) |
Balance at March 31, 2012 |  |  | 872,032 |  |  |  | 20.12 |
Granted |  |  | — |  |  |  | — |
Exercised |  |  | — |  |  |  | — |
Cancelled |  |  | (17,074 | ) |  |  | 13.22 |
Outstanding options at June 30, 2012 |  |  | 854,958 |  |  |  | 20.26 |
Summary of changes in unvested options |
|  | Number of options |  |  | Weighted-average exercise price ($) |  |  | Weighted-average grant date fair value ($) |
Unvested options at March 31, 2012 |  |  | 133,904 |  |  |  | 11.66 |  |  |  | 9.34 |
Granted |  |  | — |  |  |  | — |  |  |  | — |
Vested |  |  | (18,079 | ) |  |  | 12.13 |  |  |  | 9.79 |
Cancelled |  |  | (11,832 | ) |  |  | 11.96 |  |  |  | 9.12 |
Unvested options at June 30, 2012 |  |  | 103,993 |  |  |  | 11.54 |  |  |  | 9.28 |
Summary of changes in unvested restricted stock units |
|  | Number of RSUs |  |  | Weighted-average grant date fair value ($) |
Unvested restricted stock units at March 31, 2012 |  |  | 1,542,675 |  |  |  | 2.95 |
Granted(1) |  |  | 54,000 |  |  |  | 0.82 |
Vested |  |  | (118,862 | ) |  |  | 11.45 |
Cancelled |  |  | (10,280 | ) |  |  | 12.17 |
Balance unvested at June 30, 2012 |  |  | 1,467,533 |  |  |  | 2.12 |
(1) | 34,000 of these restricted stock units vest and convert into shares of our common stock after one year from the date of grant. 20,000 of these restricted stock units will vest and convert into shares of our common stock over a four year period from the date of grant; one-fourth of the award will vest on each grant date anniversary following the grant.
Summary of changes in Stock appreciation rights |
|  | Number of SARs |
Outstanding at March 31, 2012 |  |  | 115,187 |
Granted |  |  | — |
Exercised |  |  | — |
Forfeited and expired |  |  | — |
Outstanding SARs at June 30, 2012 |  |  | 115,187 |
SARs exercisable at June 30, 2012 |  |  | 115,187 |

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