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Stock-Based Compensation (Details) (USD $)	3 Months Ended		6 Months Ended
Stock-Based Compensation (Details) (USD $)	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total employee stock-based compensation expense	$ 723,445	$ 1,014,263	$ 1,459,990	$ 1,948,727
Effect on basic and diluted net income (loss) per share	$ (0.03)	$ (0.07)	$ (0.06)	$ (0.14)
Research and development expense [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total employee stock-based compensation expense	320,303	522,958	652,177	961,001
Selling, general and administrative expense [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total employee stock-based compensation expense	$ 403,142	$ 491,305	$ 807,813	$ 987,726

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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