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Income Taxes (Details 1) (USD $) | Dec. 31, 2012 | Dec. 31, 2011
--- | --- | ---
Deferred tax assets: |  |
Capitalized research and development costs | $ 53,824,000 | $ 53,565,000
Net operating losses | 53,687,000 | 53,065,000
Research and development credits | 7,777,000 | 8,038,000
Accrued wind down cost | 292,000 | 630,000
Stock-based compensation | 853,000 | 512,000
Capital loss carryover | 544,000 | 596,000
Fixed assets | 430,000 | 458,000
Other | 1,002,000 | 731,000
Gross Deferred Tax assets | 118,409,000 | 117,595,000
Valuation allowance | (118,045,000) | (117,181,000)
Total deferred tax assets | 364,000 | 414,000
Deferred tax liability: |  |
Intangible assets | (364,000) | (414,000)
Total deferred tax liability | (364,000) | (414,000)
Net deferred tax assets |  |

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