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Consolidated Statement of Stockholder's Equity (USD $) | Total | Common Stock | Additional Paid-in Capital | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2009 | $ 30,495,067 |  | $ 118,349 | $ 316,009,930 | $ (286,027,935) | $ 394,723
Beginning Balance, Shares at Dec. 31, 2009 |  |  | 11,834,958 |  |  |
Net loss | (25,243,551) |  |  |  | (25,243,551) |
Unrealized gain (loss) on foreign currency translation | (268,810) |  |  |  |  | (268,810)
Change in unrealized gain (loss) on securities available-for-sale | (6,191) |  |  |  |  | (6,191)
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively, shares |  |  | 847,520 |  |  |
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively | 7,279,234 |  | 8,475 | 7,270,759 |  |
Common stock issued pursuant to employee benefit plan, shares |  |  | 18,488 |  |  |
Common stock issued pursuant to employee benefit plan | 232,229 |  | 185 | 232,044 |  |
Compensation expense from grant of options, restricted stock units and stock (fair value) | 3,697,405 |  |  | 3,697,405 |  |
Exercise of employee and director stock options, shares | 3,451 |  | 3,451 |  |  |
Exercise of employee and director stock options | 19,802 |  | 35 | 19,767 |  |
Exercise and net settlement of restricted stock units, shares |  |  | 53,370 |  |  |
Exercise and net settlement of restricted stock units | (483,406) |  | 534 | (483,940) |  |
Stock retired from settlement agreement, shares |  |  | (26,500) |  |  |
Stock retired from settlement agreement | (241,150) | [1] | (265) | (240,885) |  |
Ending Balance at Dec. 31, 2010 | 15,480,629 |  | 127,313 | 326,505,080 | (311,271,486) | 119,722
Ending Balance, Shares at Dec. 31, 2010 |  |  | 12,731,287 |  |  |
Net loss | (21,328,536) |  |  |  | (21,328,536) |
Unrealized gain (loss) on foreign currency translation | 40,032 |  |  |  |  | 40,032
Change in unrealized gain (loss) on securities available-for-sale | (119,041) |  |  |  |  | (119,041)
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively, shares |  |  | 9,525,116 |  |  |
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively | 13,792,340 |  | 95,251 | 13,697,089 |  |
Common stock issued pursuant to employee benefit plan, shares |  |  | 35,164 |  |  |
Common stock issued pursuant to employee benefit plan | 164,896 |  | 352 | 164,544 |  |
Compensation expense from grant of options, restricted stock units and stock (fair value), shares |  |  | 32,631 |  |  |
Compensation expense from grant of options, restricted stock units and stock (fair value) | 3,096,043 |  | 326 | 3,095,717 |  |
Exercise of employee and director stock options, shares | 1,692 |  | 1,692 |  |  |
Exercise of employee and director stock options | 2,386 |  | 17 | 2,369 |  |
Exercise and net settlement of restricted stock units, shares |  |  | 102,065 |  |  |
Exercise and net settlement of restricted stock units | (403,625) |  | 1,021 | (404,646) |  |
Ending Balance at Dec. 31, 2011 | 10,725,124 |  | 224,280 | 343,060,153 | (332,600,022) | 40,713
Ending Balance, Shares at Dec. 31, 2011 |  |  | 22,427,955 |  |  |
Net loss | (28,491,153) |  |  |  | (28,491,153) |
Unrealized gain (loss) on foreign currency translation | 151,125 |  |  |  |  | 151,125
Change in unrealized gain (loss) on securities available-for-sale | 1,339 |  |  |  |  | 1,339
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively, shares |  |  | 14,546,042 |  |  |
Issuance of common stock and warrants, net of issuance cost of $480,835, $1,522,083 and $900,992 in 2010, 2011 and 2012 respectively | 28,725,507 |  | 145,460 | 28,580,047 |  |
Common stock for external services, shares |  |  | 102,058 |  |  |
Common stock for external services | 175,235 |  | 1,021 | 174,214 |  |
Common stock issued pursuant to employee benefit plan, shares |  |  | 129,893 |  |  |
Common stock issued pursuant to employee benefit plan | 97,017 |  | 1,299 | 95,718 |  |
Compensation expense from grant of options, restricted stock units and stock (fair value), shares |  |  | 182,502 |  |  |
Compensation expense from grant of options, restricted stock units and stock (fair value) | 2,655,884 |  | 1,825 | 2,654,059 |  |
Exercise of employee and director stock options, shares | 3,629 |  | 3,629 |  |  |
Exercise of employee and director stock options | 3,629 |  | 36 | 3,593 |  |
Exercise and net settlement of restricted stock units, shares |  |  | 114,226 |  |  |
Exercise and net settlement of restricted stock units | (59,090) |  | 1,142 | (60,232) |  |
Ending Balance at Dec. 31, 2012 | $ 13,984,617 |  | $ 375,063 | $ 374,507,552 | $ (361,091,175) | $ 193,177
Ending Balance, Shares at Dec. 31, 2012 |  |  | 37,506,305 |  |  |
[1] | On April 1, 2009, we acquired the operations of Stem Cell Sciences Plc (SCS), which changed its name to Asset Realization Company Limited. Pursuant to the acquisition agreement, 53,000 shares were placed into an escrow for a twelve month period to satisfy any indemnification obligations owed to us by SCS. On August 19, 2010, we entered into a settlement agreement with SCS in which the parties agreed to the release of half the escrowed shares to SCS and half to us in full satisfaction of our claims for indemnification, and both parties waived all other claims, known and unknown, against the other. The 26,500 shares returned to us are being treated as retired and no longer outstanding. We have recorded approximately $227,000 as other income, which was the value of these shares based on the closing price of $9.10 per share on August 19, 2010, and net of amounts already accrued for potential claims against the escrowed shares.

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