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Summary of Significant Accounting Policies (Details 1) (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Basic and dilutive net loss per share computations      
Net loss $ (28,491,153) $ (21,328,536) $ (25,243,551)
Weighted average shares outstanding used to compute basic and diluted net loss per share 28,824,417 14,187,885 12,330,299
Basic and diluted net loss per share $ (0.99) $ (1.50) $ (2.05)