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Income Taxes (Details Textual) (USD $)
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Income Taxes (Additional Textual) [Abstract]      
Unrecognized tax benefits $ 0 $ 0  
Increase in valuation allowances 864,000 7,871,000 7,030,000
Tax liabilities 0    
Tax related interest 0    
Tax related penalties 0    
Decrease in state deferred income taxes 5,000,000    
Research and development [Member]
      
Income Taxes (Textual) [Abstract]      
Credit research expiry date Dec. 31, 2011    
Credit research expiry extended date Jan. 01, 2014    
Research deferred tax carryforward amount 400,000    
Domestic Tax Authority [Member]
      
Income Taxes (Textual) [Abstract]      
Net operating loss carryforward 143,909,000    
Operating loss carryforward expiration period description 2018 through 2032    
Domestic Tax Authority [Member] | Research and development [Member]
      
Income Taxes (Textual) [Abstract]      
Research and development tax credits 4,846,000    
Operating loss carryforward expiration period description 2018 through 2031    
State and Local Jurisdiction [Member]
      
Income Taxes (Textual) [Abstract]      
Net operating loss carryforward 47,105,000    
Operating loss carryforward expiration period description 2013 through 2032    
State and Local Jurisdiction [Member] | Research and development [Member]
      
Income Taxes (Textual) [Abstract]      
Research and development tax credits 4,441,000    
State research and development tax credits net of federal tax effect 2,931,000    
Foreign Tax Authority [Member]
      
Income Taxes (Textual) [Abstract]      
Net operating loss carryforward 11,713,000    
Domestic and State [Member] | Capital Loss Carryforward [Member]
      
Income Taxes (Textual) [Abstract]      
Capital loss carry forward for federal and state income tax purposes $ 1,592,000    
Operating loss carryforward expiration period description 2014 through 2016