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Subsequent Events (Details Textual) (USD $)
 1 Months Ended 6 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended
Mar. 31, 2013
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Jan. 31, 2011
Jun. 30, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Feb. 28, 2013
Subsequent Event [Member]
Dec. 31, 2012
Subsequent Event [Member]
Subsequent events (Textual) [Abstract]                
Number of shares of common stock       2,700,000     782,755  
Sale of stock, price per share   $ 10.00   $ 2.12 $ 2.47 $ 11.60 $ 2.06  
Gross proceeds from common stock   $ 9,400,000   $ 19,747,550 $ 19,774,820 $ 7,279,234 $ 1,616,000  
Sales agent is paid compensation equal to 3% of gross proceeds       3.00% 3.00% 3.00%   3.00%
Warrant exercise shares             324,534  
Warrant exercise price             1.40  
Proceeds from the exercise of warrants     3,375,000 6,256,438     454,000  
Warrant common stock share issued             324,534  
Commercial lease agreement of office and research space 18,700              
Initial term of lease 10 years              
Initial term aggregate as rent over term of lease $ 3,500,000