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Condensed Consolidated Statements of Operations (Unaudited) (USD $)
 3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Revenue:    
Revenue from licensing agreements, grants and other $ 75,642 $ 372,677
Revenue from product sales 208,558 271,359
Total revenue 284,200 644,036
Cost of product sales 66,841 71,959
Gross profit 217,359 572,077
Operating expenses:    
Research and development 4,563,890 3,938,391
Selling, general and administrative 1,887,757 1,924,325
Wind-down expenses 22,859 35,155
Total operating expenses 6,474,506 5,897,871
Loss from operations (6,257,147) (5,325,794)
Other income (expense):    
Change in fair value of warrant liability (188,607) (4,941,177)
Interest income 6,846 4,210
Interest expense (10,148) (14,447)
Other income (expense), net 32,609 47,769
Total other income (expense), net (159,300) (4,903,645)
Net loss $ (6,416,447) $ (10,229,439)
Basic and diluted net loss per share $ (0.17) $ (0.45)
Weighted average number of common shares outstanding, basic and diluted 38,263,434 22,958,498