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Condensed Consolidated Statements of Operations (USD $)
 3 Months Ended 9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Revenue:        
Revenue from licensing agreements, grants and other $ 52,798 $ 60,739 $ 159,773 $ 471,501
Revenue from product sales 271,994 203,256 730,916 685,364
Total revenue 324,792 263,995 890,689 1,156,865
Cost of product sales 85,743 71,891 230,157 208,127
Gross profit 239,049 192,104 660,532 948,738
Operating expenses:        
Research and development 5,184,365 3,478,142 14,553,145 11,165,599
Selling, general and administrative 1,710,749 1,636,438 5,180,027 5,336,105
Wind-down expenses   154,742 61,837 199,799
Total operating expenses 6,895,114 5,269,322 19,795,009 16,701,503
Loss from operations (6,656,065) (5,077,218) (19,134,477) (15,752,765)
Other income (expense):        
Change in fair value of warrant liability (143,511) (11,239,465) 425,570 (9,974,685)
Interest income 136 2,372 8,772 9,393
Interest expense (382,119) (11,392) (785,122) (40,014)
Other income (expense), net (10,094) (11,087) 8,475 25,364
Total other expense, net (535,588) (11,259,572) (342,305) (9,979,942)
Net loss $ (7,191,653) $ (16,336,790) $ (19,476,782) $ (25,732,707)
Basic and diluted net loss per share $ (0.17) $ (0.54) $ (0.49) $ (0.99)
Weighted average number of common shares outstanding, basic and diluted 41,402,717 30,168,475 39,787,527 25,992,764