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Condensed Consolidated Statements of Cash Flows (unaudited) (USD $) | 6 Months Ended
--- | ---
Jun. 30, 2014 | Jun. 30, 2013
Cash flows from operating activities: |  |  |  |
Net loss | $ (19,735,480) |  | $ (12,285,129) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |
Depreciation and amortization | 671,562 |  | 471,558 |
Stock-based compensation | 1,034,766 |  | 1,436,223 |
Amortization of debt discount and issuance costs | 136,873 |  | 91,450 |
Gain on disposal of fixed assets | 5,671 |  | (34,946) |
Change in fair value of warrant liability | 3,981,094 |  | (569,081) |
Changes in operating assets and liabilities: |  |  |  |
Accrued interest and other receivables | 366,487 |  | (68,912) |
Trade receivables | 23,693 |  | 34,401 |
Prepaid and other current assets | (170,663) |  | 76,763 |
Other assets, non-current | 17,207 |  | (106,548) |
Accounts payable and accrued expenses | (583,429) |  | 1,292,596 |
Accrued wind-down expenses |  |  | (1,102,762) |
Deferred revenue | (31,763) |  | (57,758) |
Deferred rent | 6,797 |  | 392,057 |
Net cash used in operating activities | (14,277,185) |  | (10,430,088) |
Cash flows from investing activities: |  |  |  |
Purchase of marketable securities |  |  | (549,603) |
Proceeds from the sale and maturity of marketable securities |  |  | 13,026,000 |
Purchases of property, plant and equipment | (362,873) |  | (2,420,430) |
Proceeds from sale of property, plant and equipment |  |  | 38,500 |
Acquisition of other assets |  |  | (100,000) |
Net cash provided by (used in) investing activities | (362,873) |  | 9,994,467 |
Cash flows from financing activities: |  |  |  |
Proceeds from issuance of common stock, net of issuance costs | 279,084 |  | 4,911,627 |
Proceeds from the exercise of stock options |  |  | 2,086 |
Proceeds from the exercise of warrants, net of issuance costs | 316,350 |  | 460,762 |
Proceeds from loan payable, net of issuance costs | 3,820,264 |  | 9,783,094 |
Payments related to net share issuance of stock based awards | (499,333) |  | (330,351) |
Repayment of capital lease obligations | (10,466) |  | (3,382) |
Repayment of loan and bond payable | (2,007,457) |  | (100,000) |
Net cash provided by financing activities | 1,898,442 |  | 14,723,836 |
Increase (decrease) in cash and cash equivalents | (12,741,616) |  | 14,288,215 |
Effects of foreign exchange rate changes on cash | 3,289 |  | (6,595) |
Cash and cash equivalents, beginning of period | 30,585,424 |  | 8,471,275 |
Cash and cash equivalents, end of period | 17,847,097 |  | 22,752,895 |
Supplemental disclosure of cash flow information: |  |  |  |
Interest paid | 272,478 |  | 110,266 |
Fair value of 329,131 shares issued as consideration under an equity financing agreement |  | [1] | $ 600,006 | [1]
[1] | In June 2013, we entered into an agreement with an institutional investor, under which we have the right to sell up to $30.0 million of common stock to the institutional investor. In consideration for entering into the agreement, we issued 329,131 shares of our common stock to the institutional investor. We will not receive any cash proceeds from the issuance of these 329,131 shares. All shares sold or to be sold under this agreement are offered under our shelf registration statement previously filed with, and declared effective by, the SEC. In October 2013, we terminated the agreement without any cost or penalty.

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- Definition The cash inflow associated with the aggregate amount received by the entity through sale or maturity of marketable securities (held-to-maturity or available-for-sale) during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=6871852&loc=d3e26853-111562 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 + Details
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- Definition The cash inflow from the sale of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock options. This item inherently excludes any excess tax benefit, which the entity may have realized and reported separately. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (j) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock warrants. + References No definition available. + Details
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- Definition The cash outflow for the obligation for a lease meeting the criteria for capitalization (with maturities exceeding one year or beyond the operating cycle of the entity, if longer). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3291-108585 + Details
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- Definition The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3291-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition The fair value of stock issued in noncash financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=6367179&loc=d3e4332-108586 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=6367179&loc=d3e4313-108586 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=6367179&loc=d3e4304-108586 + Details
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