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Condensed Consolidated Statements of Operations (Unaudited) (USD $)
 3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Revenue:        
Revenue from licensing agreements, grants and other $ 23,479 $ 31,333 $ 47,063 $ 106,975
Revenue from product sales 218,725 250,364 534,621 458,922
Total revenue 242,204 281,697 581,684 565,897
Cost of product sales 78,097 77,573 165,373 144,414
Gross profit 164,107 204,124 416,311 421,483
Operating expenses:        
Research and development 6,092,284 4,804,890 10,996,578 9,368,780
Selling, general and administrative 2,175,797 1,581,521 4,423,397 3,469,278
Wind-down expenses    38,978    61,837
Total operating expenses 8,268,081 6,425,389 15,419,975 12,899,895
Loss from operations (8,103,974) (6,221,265) (15,003,664) (12,478,412)
Other income (expense):        
Change in fair value of warrant liability (3,654,470) 757,688 (3,981,094) 569,081
Interest income 1,689 1,790 3,874 8,636
Interest expense (343,224) (392,855) (723,712) (403,003)
Other income (expense), net (15,245) (14,040) (30,884) 18,569
Total other expense, net (4,011,250) 352,583 (4,731,816) 193,283
Net loss $ (12,115,224) $ (5,868,682) $ (19,735,480) $ (12,285,129)
Basic and diluted net loss per share $ (0.22) $ (0.15) $ (0.36) $ (0.32)
Weighted average number of common shares outstanding, basic and diluted 55,711,717 39,661,934 55,529,818 38,966,547