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Condensed Consolidated Statements of Cash Flows (unaudited) (USD $)
6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Cash flows from operating activities:    
Net loss $ (19,735,480) $ (12,285,129)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 671,562 471,558
Stock-based compensation 1,034,766 1,436,223
Amortization of debt discount and issuance costs 136,873 91,450
Gain on disposal of fixed assets 5,671 (34,946)
Change in fair value of warrant liability 3,981,094 (569,081)
Changes in operating assets and liabilities:    
Accrued interest and other receivables 366,487 (68,912)
Trade receivables 23,693 34,401
Prepaid and other current assets (170,663) 76,763
Other assets, non-current 17,207 (106,548)
Accounts payable and accrued expenses (583,429) 1,292,596
Accrued wind-down expenses    (1,102,762)
Deferred revenue (31,763) (57,758)
Deferred rent 6,797 392,057
Net cash used in operating activities (14,277,185) (10,430,088)
Cash flows from investing activities:    
Purchase of marketable securities    (549,603)
Proceeds from the sale and maturity of marketable securities    13,026,000
Purchases of property, plant and equipment (362,873) (2,420,430)
Proceeds from sale of property, plant and equipment    38,500
Acquisition of other assets    (100,000)
Net cash provided by (used in) investing activities (362,873) 9,994,467
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs 279,084 4,911,627
Proceeds from the exercise of stock options    2,086
Proceeds from the exercise of warrants, net of issuance costs 316,350 460,762
Proceeds from loan payable, net of issuance costs 3,820,264 9,783,094
Payments related to net share issuance of stock based awards (499,333) (330,351)
Repayment of capital lease obligations (10,466) (3,382)
Repayment of loan and bond payable (2,007,457) (100,000)
Net cash provided by financing activities 1,898,442 14,723,836
Increase (decrease) in cash and cash equivalents (12,741,616) 14,288,215
Effects of foreign exchange rate changes on cash 3,289 (6,595)
Cash and cash equivalents, beginning of period 30,585,424 8,471,275
Cash and cash equivalents, end of period 17,847,097 22,752,895
Supplemental disclosure of cash flow information:    
Interest paid 272,478 110,266
Fair value of 329,131 shares issued as consideration under an equity financing agreement    [1] $ 600,006 [1]
[1] In June 2013, we entered into an agreement with an institutional investor, under which we have the right to sell up to $30.0 million of common stock to the institutional investor. In consideration for entering into the agreement, we issued 329,131 shares of our common stock to the institutional investor. We will not receive any cash proceeds from the issuance of these 329,131 shares. All shares sold or to be sold under this agreement are offered under our shelf registration statement previously filed with, and declared effective by, the SEC. In October 2013, we terminated the agreement without any cost or penalty.