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Stock-Based Compensation - Stock-Based Compensation Expense (Detail) (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense and effect on net loss $ 508,811 $ 597,005 $ 1,543,577 $ 2,033,228
Effect on basic and diluted net loss per share $ (0.01) $ (0.01) $ (0.03) $ (0.05)
Research and development expense [Member]
       
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense and effect on net loss 188,357 346,938 414,246 1,064,301
Selling, general and administrative expense [Member]
       
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense and effect on net loss $ 320,454 $ 250,067 $ 1,129,331 $ 968,927