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Condensed Consolidated Statements of Cash Flows (unaudited) (USD $)
9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Cash flows from operating activities:    
Net loss $ (22,492,666) $ (19,476,782)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 992,612 730,504
Stock-based compensation 1,543,577 2,033,228
Amortization of debt discount and issuance costs 192,117 509,069
Loss (gain) on disposal of fixed assets 8,845 (34,946)
Change in fair value of warrant liability (95,266) (425,570)
Changes in operating assets and liabilities:    
Accrued interest and other receivables 277,173 (364,940)
Trade receivables 37,121 57,569
Prepaid and other current assets (483,178) 782,745
Other assets, non-current 17,207 (52,474)
Accounts payable and accrued expenses (911,327) 499,935
Accrued wind-down expenses   (1,102,762)
Deferred revenue (52,291) (19,146)
Deferred rent 5,500 431,390
Net cash used in operating activities (20,960,576) (16,432,180)
Cash flows from investing activities:    
Purchase of marketable securities   (527,967)
Proceeds from the sale and maturity of marketable securities   14,430,000
Purchases of property, plant and equipment (598,432) (4,556,406)
Proceeds from sale of property, plant and equipment   38,500
Acquisition of other assets   (100,000)
Net cash provided by (used in) investing activities (598,432) 9,284,127
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs 18,952,721 6,115,442
Proceeds from the exercise of stock options   2,809
Proceeds from the exercise of warrants, net of issuance costs 1,974,931 460,097
Proceeds from loan payable, net of issuance costs 5,775,543 13,558,358
Payments related to net share issuance of stock based awards (499,333) (342,366)
Repayment of capital lease obligations (15,842) (7,302)
Repayment of loan and bond payable (2,996,204) (152,500)
Net cash provided by financing activities 23,191,816 19,634,538
Increase (decrease) in cash and cash equivalents 1,632,808 12,486,485
Effects of foreign exchange rate changes on cash (5,643) (2,467)
Cash and cash equivalents, beginning of period 30,585,424 8,471,275
Cash and cash equivalents, end of period 32,212,589 20,955,293
Supplemental disclosure of cash flow information:    
Interest paid 384,545 271,054
Fair value of 329,131 shares issued as consideration under an equity financing agreement   600,006 [1]
Equipment acquired under a capital lease   $ 43,600 [2]
[1] In June 2013, we entered into an agreement with an institutional investor, under which we have the right to sell up to $30.0 million of common stock to the institutional investor. In consideration for entering into the agreement, we issued 329,131 shares of our common stock to the institutional investor. We will not receive any cash proceeds from the issuance of these 329,131 shares. All shares sold or to be sold under this agreement are offered under our shelf registration statement previously filed with, and declared effective by, the SEC. In October 2013, we terminated the agreement without any cost or penalty.
[2] Represents the present value of future minimum capital lease payments for equipment leased.