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Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Stock-Based Compensation Expense

Our stock-based compensation expense for the three and nine months ended September 30 was as follows:

 

     Three months ended      Nine months ended  
   September 30,      September 30,  
     2015      2014      2015      2014  

Research and development expense

   $ 781,791       $ 188,357       $ 2,063,499       $ 414,246   

General and administrative expense

     644,451         320,454         2,023,211         1,129,331   
  

 

 

    

 

 

       

 

 

 

Total stock-based compensation

   $ 1,426,242       $ 508,811       $ 4,086,710       $ 1,543,577   
  

 

 

    

 

 

    

 

 

    

 

 

 

Effect on basic and diluted net loss per share

   $ (0.01    $ (0.01    $ (0.04    $ (0.03
Stock Option Activity

A summary of our stock option activity for the three months ended September 30, 2015 is as follows:

 

     Number of options      Weighted-average
exercise price ($) per share
 

Outstanding options at June 30, 2015

     2,765,229         2.49   

Granted1

     105,000         0.43   

Exercised

     —          —    

Cancelled

     (76,000      1.39   
  

 

 

    

Outstanding options at September 30, 2015

     2,794,229         2.44   
  

 

 

    

 

Summary of Changes in Unvested Options

A summary of changes in unvested options for the three months ended September 30, 2015 is as follows:

 

     Number of options     

Weighted-average exercise

price ($) per share

    

Weighted-average grant date

fair value ($) per option

 

Unvested options at June 30, 2015

     2,490,000        0.70        0.46  

Granted

     105,000         0.43         0.28   

Vested

     —          —          —    

Cancelled

     (75,000 )      0.71        0.49  
  

 

 

    

 

 

    

 

 

 

Unvested options at September 30, 2015

     2,520,000         0.69         0.45   
Summary of Changes in Restricted Stock Unit Activity

A summary of changes in our restricted stock units for the three months ended September 30, 2015 is as follows:

 

     Number of RSUs      Weighted Average
Grant Date
Fair Value ($)
 

Outstanding at June 30, 2015

     9,358,518         1.22   

Granted2

     100,000         0.41   

Vested and exercised

     (87,500      1.93   

Cancelled

     (108,500      1.14   
  

 

 

    

Outstanding at September 30, 2015

     9,262,518         1.20