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Consolidated Statement of Stockholders' Equity (Deficit) - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
AOCI Attributable to Parent [Member]
Beginning Balance at Dec. 31, 2012 $ 13,984,617 $ 375,063 $ 374,507,552 $ (361,091,175) $ 193,177
Beginning Balance, Shares at Dec. 31, 2012   37,506,305      
Net loss (26,439,159)     $ (26,439,159)  
Unrealized gain on foreign currency translation 57,568       57,568
Change in unrealized gain on securities available-for-sale 1,356       $ 1,356
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively 24,879,573 $ 169,385 24,710,188    
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively, Shares   16,938,575      
Common stock issued for external services 154,111 $ 1,049 153,062    
Common stock issued for external services, shares   104,911      
Common stock issued pursuant to employee benefit plan 132,071 $ 829 131,242    
Common stock issued pursuant to employee benefit plan, shares   82,863      
Compensation expense from grant of options and restricted stock units (fair value) 2,322,489   $ 2,322,489    
Compensation expense from grant of options, restricted stock units and stock (fair value), shares   0 0 0 0
Exercise of director stock options $ 3,452 $ 35 $ 3,417    
Exercise of director stock options, shares 3,452 3,452      
Exercise and net settlement of restricted stock units $ (342,366) $ 3,627 (345,993)    
Exercise and net settlement of restricted stock units, shares   362,657      
Common stock issued as consideration in the acquisition of a patent portfolio 200,000 $ 1,395 198,605    
Common stock issued as consideration in the acquisition of a patent portfolio, shares   139,548      
Ending Balance at Dec. 31, 2013 14,953,712 $ 551,383 401,680,562 $ (387,530,334) $ 252,101
Ending Balance, Shares at Dec. 31, 2013   55,138,311      
Net loss (32,741,274)     $ (32,741,274)  
Unrealized gain on foreign currency translation (186,711)       $ (186,711)
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively 22,359,386 $ 128,522 22,230,864    
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively, Shares   12,852,221      
Common stock issued for external services 154,708 $ 1,202 153,506    
Common stock issued for external services, shares   120,149      
Common stock issued pursuant to employee benefit plan 183,677 $ 1,157 182,520    
Common stock issued pursuant to employee benefit plan, shares   115,722      
Compensation expense from grant of options and restricted stock units (fair value) $ 1,646,608   $ 1,646,608    
Compensation expense from grant of options, restricted stock units and stock (fair value), shares   0 0 0 0
Exercise of director stock options, shares 0        
Exercise and net settlement of restricted stock units $ (499,333) $ 5,034 $ (504,367)    
Exercise and net settlement of restricted stock units, shares   503,371      
Ending Balance at Dec. 31, 2014 5,870,773 $ 687,298 425,389,693 $ (420,271,608) $ 65,390
Ending Balance, Shares at Dec. 31, 2014   68,729,774      
Net loss (36,415,026)     $ (36,415,026)  
Unrealized gain on foreign currency translation (18,031)       $ (18,031)
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively 26,324,565 $ 410,190 25,914,375    
Issuance of common stock and warrants, net of issuance cost of $2,051,699, $1,335,327 and $2,015,808 in 2013, 2014 and 2015 respectively, Shares   41,018,931      
Common stock issued for external services 232,001 $ 4,222 227,779    
Common stock issued for external services, shares   422,207      
Common stock issued pursuant to employee benefit plan 230,265 $ 3,550 226,715    
Common stock issued pursuant to employee benefit plan, shares   355,004      
Compensation expense from grant of options and restricted stock units (fair value) $ 3,833,830   $ 3,833,830    
Compensation expense from grant of options, restricted stock units and stock (fair value), shares   0 0 0 0
Exercise of director stock options, shares 0        
Exercise and net settlement of restricted stock units $ (392,587) $ 8,223 $ (400,810)    
Exercise and net settlement of restricted stock units, shares   822,325      
Ending Balance at Dec. 31, 2015 $ (334,210) $ 1,113,483 $ 455,191,582 $ (456,686,634) $ 47,359
Ending Balance, Shares at Dec. 31, 2015   111,348,241