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Loan Payable - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended 14 Months Ended
Feb. 28, 2015
Apr. 30, 2013
Dec. 31, 2015
Aug. 31, 2014
Apr. 30, 2015
Dec. 31, 2014
Jul. 31, 2014
Oct. 31, 2013
Debt Instrument [Line Items]                
Loan term     3 years          
Annual interest rate on loan     6.00%          
Final fee payment at the end of loan term     $ 1,000,000          
Exercise price of warrants         $ 0.85   $ 2.17 $ 1.80
Initial carrying amount assigned to loan, net of discount     9,512,000          
Fair value allocated to warrant     388,000          
Note issuance costs     $ 117,000          
Deferred financing costs, discount and accretion percentage     9.00%          
Common Stock [Member]                
Debt Instrument [Line Items]                
Number of shares of common stock acquired using warrant           1,180,015    
Silicon Valley Bank Loan Agreement Warrant [Member]                
Debt Instrument [Line Items]                
Term of warrant     10 years          
Exercise price of warrants     $ 1.7034          
Warrant expiration period     2023-04          
Silicon Valley Bank Loan Agreement Warrant [Member] | Common Stock [Member]                
Debt Instrument [Line Items]                
Number of shares of common stock acquired using warrant     293,531          
Silicon Valley Bank Loan Agreement [Member]                
Debt Instrument [Line Items]                
Proceeds from loan   $ 9,900,000            
Cash discount   100,000 $ 100,000          
Loan term     3 years          
Annual interest rate on loan     6.00%          
Period of loan subject to interest payments only     6 months          
Period of loan subject to principal and interest payments     30 months          
Final fee payment at the end of loan term     $ 1,000,000          
Proceeds received under loan agreement     9,900,000          
Initial carrying amount assigned to loan, net of discount     9,512,000          
Fair value allocated to warrant     388,000          
Note issuance costs     $ 117,000          
Deferred financing costs, discount and accretion percentage     9.00%          
Minimum cash proceeds from investors required to release pledged restricted money market account     $ 18,000,000          
Silicon Valley Bank Loan Agreement [Member] | Restricted Money Market Account [Member]                
Debt Instrument [Line Items]                
Debt instrument, collateral amount     2,422,500          
CIRM Loan Agreement [Member]                
Debt Instrument [Line Items]                
Approval of fund by California Institute for Regenerative Medicine (CIRM)   $ 19,300,000            
Aggregate proceeds from disbursement of the loan       $ 9,600,000        
Forgiveness of loan principal     8,917,000          
Accrued interest forgiven     $ 243,000          
Repayment of aggregate loan proceeds received $ 679,000