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Loan Payable - Summary of Changes in Carrying Value of Loan Payable (Detail) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2015
Dec. 31, 2014
Debt Instrument [Line Items]      
Carrying value of loan payable (current and non-current) Beginning Balance $ 15,020,417    
Repayment of principal   $ (4,778,485)  
Accretion of discount 92,097    
Carrying value of loan payable (current and non-current) Ending Balance 10,334,029    
Carrying value of loan payable, current portion   1,417,388 $ 4,686,388
Carrying value of loan payable, non-current portion   8,916,641 10,334,029
Total loan payable 15,020,417 10,334,029 15,020,417
CIRM [Member]      
Debt Instrument [Line Items]      
Carrying value of loan payable (current and non-current) Beginning Balance 9,595,807    
Repayment of principal   (679,166)  
Carrying value of loan payable (current and non-current) Ending Balance 8,916,641    
Carrying value of loan payable, non-current portion   8,916,641  
Total loan payable 9,595,807 8,916,641 9,595,807
Silicon Valley Bank Loan Agreement [Member]      
Debt Instrument [Line Items]      
Carrying value of loan payable (current and non-current) Beginning Balance 5,424,610    
Repayment of principal   (4,099,319)  
Accretion of discount 92,097    
Carrying value of loan payable (current and non-current) Ending Balance 1,417,388    
Carrying value of loan payable, current portion   1,417,388  
Total loan payable $ 5,424,610 $ 1,417,388 $ 5,424,610