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v3.5.0.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) | 9 Months Ended
--- | ---
Sep. 30, 2016 | Sep. 30, 2015
Cash flows from operating activities: |  |  |
Net loss |  | $ (11,293,817) | $ (27,455,062)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and amortization |  | 457,616 | 840,533
Stock-based compensation |  | 743,174 | 4,086,710
Amortization of debt discount and issuance costs |  | 6,331 | 98,988
Gain on disposal of fixed assets |  | (18,888) | (168,898)
Write-down of fixed assets |  | 3,332,736 |
Change in fair value of warrant liability |  | (1,596,554) | (1,068,626)
Conversion of CIRM loan to grant revenue |  | (8,916,641) |
Gain on extinguishment of CIRM loan |  | (242,931) |
Discount received on final settlement of vendor invoices |  | (1,875,701) |
Changes in operating assets and liabilities: |  |  |
Trade receivables |  |  | 152,877
Other receivables |  | 29,459 | 113,746
Prepaid and other current assets |  | 570,230 | 213,761
Other assets |  | 40,000 |
Accounts payable and accrued expenses |  | (4,345,253) | (511,188)
Accrued wind-down expense |  | (1,319,863) |
Deferred revenue |  | (12,619) | (12,619)
Deferred rent |  | (44,977) | (40,477)
Net cash used in operating activities |  | (24,487,698) | (23,750,255)
Cash flows from investing activities: |  |  |
Purchases of property, plant and equipment |  | (15,434) | (1,005,273)
Proceeds from sale of property, plant and equipment |  | 1,468,888 | 168,713
Net cash provided by (used in) investing activities |  | 1,453,454 | (836,560)
Cash flows from financing activities: |  |  |
Proceeds from the issuance of common stock, net of issuance costs |  | 7,259,613 | 24,942,963
Proceeds from exercise of warrants, net |  | 3,044,035 |
Release of restricted cash |  | 2,422,500 |
Payments related to net share issuance of stock based awards |  | (289,969) | (392,587)
Repayment of capital lease obligations |  | (11,030) | (17,764)
Proceeds from loan payable |  | 2,000,000 |
Repayment of loan payable |  | (1,422,495) | (3,730,168)
Net cash provided by financing activities |  | 13,002,654 | 20,802,444
Decrease in cash and cash equivalents |  | (10,031,590) | (3,784,371)
Effects of foreign exchange rate changes on cash |  | (357) | (17,969)
Cash and cash equivalents, beginning of period |  | 12,110,565 | 24,987,603
Cash and cash equivalents, end of period |  | 2,078,618 | 21,185,263
Supplemental disclosure of cash flow information: |  |  |
Interest paid |  | $ 40,529 | 191,895
Supplemental schedule of non-cash investing and financing activities: |  |  |
Equipment acquired under a capital lease | [1] |  | $ 28,882
[1] | Represents the present value of future minimum capital lease payment for equipment leased

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- Definition The cash inflow from the additional capital contribution to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3255-108585 + Details
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- Definition The cash inflow from a borrowing supported by a written promise to pay an obligation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition The net cash inflow or outflow from cash and cash items that are not available for withdrawal or usage. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3291-108585 + Details
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- Definition The cash inflow from the sale of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3179-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock warrants. + References No definition available. + Details
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- Definition The cash outflow for the obligation for a lease meeting the criteria for capitalization (with maturities exceeding one year or beyond the operating cycle of the entity, if longer). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3291-108585 + Details
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- Definition The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3291-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3602-108585 + Details
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