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Summary of Significant Accounting Policies - Basic and Dilutive Net Loss per Share Computations (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Accounting Policies [Abstract]        
Net loss $ (4,247,870) $ (9,642,647) $ (11,293,817) $ (27,455,062)
Weighted average shares outstanding used to compute basic and diluted net loss per share [1] 13,972,198 9,039,863 11,829,390 7,592,238
Basic and diluted net loss per share [1] $ (0.30) $ (1.07) $ (0.95) $ (3.62)
[1] Adjusted for the 1-for-12 reverse stock split as discussed in Note 1.